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Mercedes-Benz E450 Fuel Economy

EPA-verified MPG for all 36 variants (2019–2026)

26Best MPG
24Avg MPG
36Variants
8Model Years
Year Best MPG Avg MPG Variants
2026 25 MPG 25 MPG 2
2025 25 MPG 25 MPG 2
2024 25 MPG 25 MPG 2
2023 26 MPG 25 MPG 6
2022 25 MPG 25 MPG 6
2021 26 MPG 25 MPG 6
2020 23 MPG 23 MPG 6
2019 23 MPG 23 MPG 6
2026
4matic All-Terrain (wagon) 3.0L 6-cyl
25MPG combined
22 city · 31 hwy
2026
4matic 3.0L 6-cyl
25MPG combined
22 city · 31 hwy
2025
4matic All-Terrain (wagon) 3.0L 6-cyl
25MPG combined
22 city · 31 hwy
2025
4matic 3.0L 6-cyl
25MPG combined
22 city · 31 hwy
2024
4matic All-Terrain (wagon) 3.0L 6-cyl
25MPG combined
22 city · 31 hwy
2024
4matic 3.0L 6-cyl
25MPG combined
22 city · 31 hwy
2023
4matic 3.0L 6-cyl
26MPG combined
23 city · 31 hwy
2023
Coupe 3.0L 6-cyl
25MPG combined
23 city · 30 hwy
2023
Convertible 3.0L 6-cyl
25MPG combined
22 city · 29 hwy
2023
4matic Coupe 3.0L 6-cyl
24MPG combined
21 city · 30 hwy
2023
4matic Convertible 3.0L 6-cyl
24MPG combined
22 city · 29 hwy
2023
4matic All-Terrain (wagon) 3.0L 6-cyl
24MPG combined
21 city · 28 hwy
2022
4matic 3.0L 6-cyl
25MPG combined
23 city · 30 hwy
2022
Coupe 3.0L 6-cyl
25MPG combined
22 city · 29 hwy
2022
Convertible 3.0L 6-cyl
25MPG combined
22 city · 29 hwy
2022
4matic All-Terrain (wagon) 3.0L 6-cyl
24MPG combined
21 city · 28 hwy
2022
4matic Convertible 3.0L 6-cyl
24MPG combined
22 city · 29 hwy
2022
4matic Coupe 3.0L 6-cyl
24MPG combined
21 city · 30 hwy
2021
Coupe 3.0L 6-cyl
26MPG combined
23 city · 31 hwy
2021
4matic 3.0L 6-cyl
26MPG combined
23 city · 30 hwy
2021
Convertible 3.0L 6-cyl
25MPG combined
23 city · 30 hwy
2021
4matic Convertible 3.0L 6-cyl
25MPG combined
23 city · 29 hwy
2021
4matic Coupe 3.0L 6-cyl
25MPG combined
23 city · 30 hwy
2021
4matic All-Terrain (wagon) 3.0L 6-cyl
24MPG combined
22 city · 28 hwy
2020
Coupe 3.0L 6-cyl
23MPG combined
20 city · 28 hwy
2020
4matic 3.0L 6-cyl
23MPG combined
20 city · 28 hwy
2020
Convertible 3.0L 6-cyl
23MPG combined
20 city · 27 hwy
2020
4matic Coupe 3.0L 6-cyl
22MPG combined
19 city · 26 hwy
2020
4matic Convertible 3.0L 6-cyl
22MPG combined
19 city · 26 hwy
2020
4matic (station wagon) 3.0L 6-cyl
22MPG combined
19 city · 26 hwy
2019
4matic 3.0L 6-cyl
23MPG combined
20 city · 28 hwy
2019
Coupe 3.0L 6-cyl
23MPG combined
20 city · 28 hwy
2019
Convertible 3.0L 6-cyl
23MPG combined
20 city · 27 hwy
2019
4matic Coupe 3.0L 6-cyl
22MPG combined
19 city · 26 hwy
2019
4matic Convertible 3.0L 6-cyl
22MPG combined
19 city · 26 hwy
2019
4matic (station wagon) 3.0L 6-cyl
22MPG combined
19 city · 26 hwy