The 2022 Mercedes-Benz E450 4matic Convertible 3.0L 6-cyl gets 24 MPG combined, which isn’t class-leading, but is realistic for a convertible offering this much open-air enjoyment. This car isn’t focused on maximum fuel efficiency like a Prius. It’s a luxurious, all-weather convertible with a strong engine, designed for easy cruising. Buyers likely prioritize the overall driving experience over saving a few dollars at the pump.

City and highway performance

EPA estimates show 22 MPG in the city and 29 MPG on the highway, indicating balanced performance. The city number reflects frequent stops, meaning the E450’s 3.0L inline-six and nine-speed automatic transmission might not always operate at peak efficiency. The 29 MPG highway number is relevant because this car is designed for long, top-down journeys and weekend trips.

Annual fuel cost

According to the EPA, expect to spend around $2,400 per year on fuel if you own a 2022 Mercedes-Benz E450 4Matic Convertible. This assumes 15,000 miles driven annually and current national average fuel prices. Your actual fuel costs will vary with driving habits, local fuel prices, and the fuel grade you choose. This is an inherent cost of owning a vehicle in this class, and buyers should consider it.

Real-world expectations

EPA estimates are a standardized measure, but actual fuel economy varies. Hard acceleration, short trips, and idling can reduce MPG. Careful driving and highway driving can bring the numbers closer to the EPA’s estimates. Many owners find that the car achieves the specified numbers, and that they are reasonably accurate.

How it compares

The E450’s fuel economy aligns with its competitors. The BMW 440i xDrive Convertible, a direct competitor, gets around 25 MPG combined. The Audi S5 Cabriolet also achieves about 24 MPG combined, similar to the E450. Given the performance and luxury of these vehicles, small MPG differences are often less important than styling, features, and driving feel. Reviewing E450 MPG across all years provides further perspective.

Tips to maximize efficiency

Use the E450’s driving modes to your advantage. “Comfort” mode is designed for efficiency, while “Sport” prioritizes performance. Stick to Comfort whenever possible unless you need more power. Driving gently will also help; every fast acceleration lowers your MPG.

Keep your tires properly inflated. Underinflated tires increase rolling resistance, which reduces fuel economy. Check your tire pressure regularly and maintain the pressure listed on the driver’s side doorjamb.

Reduce extra weight. Remove unnecessary items from the trunk. Excess weight makes the engine work harder, hurting fuel efficiency. An example would be carrying golf clubs when you don’t plan to golf.

Plan routes carefully. Avoid traffic and frequent stops. Highway driving offers better fuel economy than city driving. Navigation apps can help identify the most efficient routes.

Regular maintenance is important. A well-maintained engine is more efficient. Follow the recommended maintenance schedule, including oil changes, air filter replacements, and spark plug inspections. See all Mercedes Benz fuel economy data for maintenance advice.