25 MPG combined is a reasonable figure for the 2024 Mercedes-Benz E450 4matic All-Terrain. This isn’t a hybrid or a dedicated efficiency machine; it’s a luxury wagon designed to capably transport a family and their gear in comfort and style, regardless of weather conditions. Those seeking maximum MPG from a Mercedes-Benz will look elsewhere. Buyers of the All-Terrain know what they want, and prioritizing all-weather capability and cargo space means accepting a compromise when it comes to fuel consumption.

City and highway performance

The EPA estimates the E450 All-Terrain will achieve 22 MPG in the city and 31 MPG on the highway. The relatively wide gap between these figures reflects the reality of its powertrain. The 3.0L inline-six is a smooth and responsive engine, but its turbocharger needs to spool up around town, impacting fuel consumption in stop-and-go driving. On the open road, the engine settles into a more efficient cruising speed, allowing the 31 MPG highway figure to become achievable. The 9-speed automatic transmission plays a crucial role here, keeping the engine in its sweet spot for both performance and efficiency.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2024 Mercedes-Benz E450 4matic All-Terrain at $2,300. This figure is based on driving 15,000 miles per year and using the national average fuel price at the time of calculation. Keep in mind that this is just an estimate. Your actual fuel costs will vary depending on your driving habits, the type of fuel you use, and local fuel prices, particularly if you opt for premium gasoline as recommended. It provides a standardized benchmark for comparing the E450 All-Terrain to its competitors.

Real-world expectations

While the EPA provides a useful benchmark, real-world fuel economy often differs. Many owners will find their combined MPG to be slightly lower than the EPA’s 25 MPG figure, especially if they frequently engage the All-Terrain’s all-wheel-drive system in adverse conditions or drive aggressively. Conversely, drivers who prioritize fuel efficiency and spend a significant amount of time on the highway might see figures closer to, or even slightly exceeding, the EPA’s estimates. The E450 MPG across all years is affected by driving style, traffic conditions, and even tire pressure.

How it compares

The E450 All-Terrain occupies a unique niche, so direct comparisons on fuel economy are limited. The Audi A6 allroad, another luxury wagon with standard all-wheel drive, achieves a similar 22 MPG combined. Those considering a crossover SUV might cross-shop the BMW X5 xDrive40i which earns 23 MPG combined. Buyers who want less gas might consider the Volvo V90 Recharge plug-in hybrid, which provides both electric range and gasoline efficiency, although at a much higher price point. The E450 All-Terrain’s fuel economy is a trade-off for its combination of luxury, utility, and all-weather capability.

Tips to maximize efficiency

Take advantage of Eco mode. The E450 All-Terrain offers different driving modes, and selecting “Eco” will optimize the engine and transmission settings for maximum fuel efficiency. This mode typically softens throttle response and encourages earlier upshifts, which can help reduce fuel consumption, especially during city driving. Before you buy, take a look at all Mercedes Benz fuel economy data to see how the E450 stacks up against other trims.

Monitor your tire pressure regularly. Underinflated tires increase rolling resistance, which reduces fuel economy. Check your tire pressure at least once a month and inflate tires to the recommended pressure listed inside the driver’s side doorjamb. The relatively large tires on the All-Terrain can have a significant impact on fuel consumption if not properly inflated.

Minimize unnecessary weight. Carrying extra cargo in the trunk or on the roof rack increases the vehicle’s weight, which requires more energy to accelerate and maintain speed. Remove any items that you don’t need to carry regularly. This is especially important for a wagon designed to haul cargo; keeping the load light pays dividends in MPG.

Drive smoothly and avoid aggressive acceleration. Rapid acceleration and hard braking consume more fuel. Anticipate traffic conditions and drive smoothly, gradually accelerating and decelerating. Using cruise control on the highway can also help maintain a consistent speed and improve fuel economy. The inline-six is responsive, but measured inputs save fuel.