23 MPG combined is acceptable, even expected, for the 2019 Mercedes-Benz E450 Coupe with its smooth 3.0L inline-six. This isn’t a hybrid grocery getter; it’s a stylish two-door that focuses on effortless power and unmistakable presence over hyper-miling. The typical E450 Coupe buyer isn’t agonizing over fuel costs; they’re considering the aesthetics, the badge, and the overall experience. Any efficiency gains are a bonus, not the primary reason for purchasing.

City and highway performance

The EPA estimates 20 MPG in the city and 28 MPG on the highway for the 2019 E450 Coupe. That 20 MPG city figure reflects typical stop-and-go traffic, where the engine’s start/stop system works to conserve fuel at red lights. The nine-speed automatic transmission really shines on the open road. At highway speeds, it allows the engine to cruise at lower RPMs, contributing to that respectable 28 MPG rating. This car is at its best for long road trips.

Annual fuel cost

The EPA estimates an annual fuel cost of $2,500 for the 2019 Mercedes-Benz E450 Coupe. This figure is based on driving 15,000 miles per year, with 55% of those miles driven in the city and 45% on the highway. It assumes current national average fuel prices. Your actual fuel costs could vary depending on your driving habits, the type of fuel you use, and local fuel prices. That $2,500 reflects the cost of driving a powerful and luxurious coupe, a cost most E450 buyers have already factored into their budget.

Real-world expectations

While the EPA provides a standardized benchmark, real-world fuel economy for the 2019 E450 Coupe will vary. Aggressive driving, frequent short trips, and consistently using Sport or Sport+ driving modes will lower fuel economy below the official estimates. A driver accelerating smoothly, using cruise control on the highway, and sticking to Comfort mode could see numbers closer to, or slightly exceeding, the EPA ratings. A lot depends on the driver.

How it compares

The BMW 440i Coupe, a direct competitor with a similar turbocharged inline-six, achieves an EPA-rated 25 MPG combined. That’s a slight edge over the E450. Moving up in price and performance, the Audi S5 Coupe, with its turbocharged V6 and standard all-wheel drive, returns a combined 24 MPG. For some buyers the all-wheel drive may balance the price difference and fuel consumption. These comparisons highlight the fuel economy tradeoffs inherent in this segment. The E450 Coupe isn’t the most efficient option, but its blend of power, luxury, and style is desirable. Check E450 MPG across all years to see how this compares to other years.

Tips to maximize efficiency

The E450 Coupe’s drive mode selector is useful. Comfort mode focuses on fuel efficiency by optimizing throttle response and shift patterns. Sport and Sport+ modes deliver sharper performance, but use more fuel. Standard driving in Comfort will make a noticeable difference.

Consistent maintenance is critical. Ensure that your E450’s tires are properly inflated, and follow the recommended service schedule for oil changes and air filter replacements. A well-maintained engine operates more efficiently. Regular maintenance will help offset some of the costs of that premium fuel.

Avoid unnecessary idling. The E450’s start/stop system is designed to shut off the engine at traffic lights and in stop-and-go traffic. While it can be disabled, leaving it active will save fuel. Every gallon counts.

Plan your routes strategically. Choosing routes that minimize stop-and-go traffic and avoid congested areas will have a positive impact on fuel economy. A smooth flow of traffic allows the engine to operate more efficiently.

Finally, consider your driving style. Smooth acceleration and gentle braking are key to maximizing fuel efficiency in any vehicle, and the E450 Coupe is no exception. Avoid aggressive driving and try to anticipate traffic flow to minimize unnecessary acceleration and deceleration. Be sure to also check all Mercedes Benz fuel economy data to see how this car compares.