A 2020 Mercedes-Benz E450 4matic Coupe isn’t bought for its 22 MPG combined fuel economy. This sleek two-door coupe prioritizes style, comfort, and effortless performance, offering a refined driving experience far from basic transportation. Buyers of this car want a refined grand tourer, so while fuel efficiency matters, it’s secondary to overall luxury and understated power.

City and highway performance

The EPA estimates the E450 Coupe gets 19 MPG in the city and 26 MPG on the highway. These numbers reflect typical stop-and-go urban driving versus steady highway speeds. The turbocharged 3.0L inline-six engine, while strong, needs more fuel when accelerating from a stop. On the open road, the engine settles into a more efficient cruise, helped by the smooth-shifting 9-speed automatic transmission. The 4matic all-wheel-drive system adds some weight and mechanical drag that can slightly reduce fuel economy, but it offers better stability in all weather.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2020 Mercedes-Benz E450 4matic Coupe at $2,650. This is based on 15,000 miles per year, using a national average fuel price for premium gasoline, which this car requires. Individual costs will change based on driving habits, local fuel prices, and how much city versus highway driving you do. If you mainly drive in urban areas, the annual fuel cost could easily be more than $2,650, while drivers taking long highway trips might see lower expenses.

Real-world expectations

EPA estimates are a benchmark, but real-world MPG often differs. Aggressive driving, frequent short trips, and idling can significantly reduce fuel economy. However, anticipating traffic, using cruise control on the highway, and proper tire inflation can help drivers get close to or slightly exceed the EPA ratings. Expect numbers within a couple of MPG of the official figures, understanding that the data is from controlled conditions.

How it compares

The E450’s fuel economy is competitive for a luxury coupe. For example, the BMW 440i xDrive Coupe gets a combined 25 MPG with its turbocharged inline-six. The Audi A5 Coupe with its turbocharged four-cylinder gets a slightly better 27 MPG combined. However, these vehicles provide a different driving experience. The E450 prioritizes a smooth, refined ride and a more luxurious interior; the BMW is known for its sharper handling; and the Audi stands out for its sleek design. Those looking at E450 MPG across all years should keep in mind these tradeoffs.

Tips to maximize efficiency

Consistent and gentle acceleration is key. The E450’s turbocharged engine is powerful, but avoiding quick bursts of speed will save gas. See changes in traffic and keep a steady pace when you can. This cuts down on hard braking and acceleration, which uses more fuel.

On the highway, use cruise control when possible. Keeping a constant speed uses less fuel than changing the throttle. The E450’s adaptive cruise control system can also help you keep a safe distance and save gas on long drives.

Make sure your tires have the right amount of air. Underinflated tires increase rolling resistance, which makes the engine work harder and reduces fuel economy. Check your tire pressure often and inflate to the levels on the sticker inside the driver’s side doorjamb.

Think about using the car’s “Eco” driving mode, if the vehicle has it. This mode changes how the throttle and transmission respond to favor fuel efficiency over all-out performance. It might slightly reduce responsiveness, but it can improve fuel consumption, especially in city driving. People who want to explore all Mercedes Benz fuel economy data may find other options to consider.