16 MPG combined isn’t going to win any awards, but for the 2015 Mercedes-Benz S600 with its smooth 6.0L V12, it’s almost beside the point. This isn’t a car people buy because they’re pinching pennies at the pump; it’s a statement purchase, a demonstration of having arrived. Think captains of industry, celebrities who value a quiet ride above all else, and those who simply demand the peak of Mercedes-Benz luxury.

City and highway performance

The EPA rates the S600 at 13 MPG in the city and 21 MPG on the highway. The city figure reflects the engine’s displacement and the sheer mass of the car it’s tasked with moving. Hurried stop-and-go driving simply drinks fuel. The highway number, while still low compared to smaller engines, is more palatable. The S600’s strong torque allows it to cruise effortlessly at highway speeds, barely breaking a sweat, and the 7-speed automatic is programmed to seek higher gears quickly, reducing fuel consumption at constant high speeds.

Annual fuel cost

According to the EPA, the estimated annual fuel cost for the 2015 Mercedes-Benz S600 is $3,600. This calculation is based on driving 15,000 miles per year and using the national average fuel price for premium gasoline. If you live in an area with higher fuel costs or drive significantly more than 15,000 miles annually, expect that number to be considerably higher. If you’re considering an S600, it’s safe to assume fuel costs are not a primary concern, but remaining informed is always wise. But for those exploring S600 MPG across all years, remember that these are just estimates, and individual results will vary.

Real-world expectations

Real-world fuel economy for the S600 will likely mirror the EPA estimates, or fall slightly below, depending on driving style. The lure of unleashing the V12’s power is strong, and frequent bursts of acceleration will decimate fuel efficiency. Gentle acceleration and anticipation of traffic flow are key to achieving anywhere near the advertised numbers. Aggressive driving in the city can easily drop the average well below 13 MPG. The key words here are “effortless” and “smoothness,” both of which are characteristics of efficient driving.

How it compares

The S600’s fuel economy is not its strong suit, even compared to other high-performance luxury sedans. The 2015 BMW 750i, with its 4.4L V8, manages 17 MPG combined. The Audi A8 with its supercharged 3.0L V6 offers 22 MPG combined. Even a V8-powered Mercedes-Benz S550 gets a significantly better 20 MPG combined, however, each of these competitors trades off character and feel to achieve their improved economy.

For some buyers, the S600’s unique blend of power and opulence simply outweighs the advantages of even a closely related model. For a broader view, explore all Mercedes Benz fuel economy data.

Tips to maximize efficiency

Gentle acceleration is important. The V12’s torque is ample, even at low RPMs. There’s no need to bury the throttle to get up to speed. Smooth, deliberate inputs will not only save fuel but also contribute to the overall sense of refinement that defines the S600’s driving experience.

Anticipate traffic flow and avoid unnecessary braking. Maintaining a consistent speed, whenever possible, minimizes fuel consumption. Leave ample following distance and look well ahead to predict when you’ll need to slow down. This approach not only saves fuel but also enhances safety.

Ensure your tires are properly inflated. Under-inflated tires increase rolling resistance, which directly impacts fuel economy. Check your tire pressures regularly and maintain them at the recommended levels specified on the door jamb sticker.

Reduce idle time. Idling consumes fuel without covering any distance. If you’re stopped for more than a minute or two, particularly in traffic, consider turning off the engine. The S600’s advanced starting system allows for quick and smooth restarts.

Consider consolidating trips. Combining multiple errands into a single trip minimizes cold starts, which are particularly fuel-intensive. Allowing the engine to reach its optimal operating temperature improves efficiency and reduces emissions.