24 MPG combined is a perfectly acceptable fuel economy figure for the 2022 Mercedes-Benz E450 4matic All-Terrain, a luxury wagon that prioritizes space, comfort, and all-weather capability over high efficiency. This isn’t a vehicle purchased by those fixated on maximizing every last mile per gallon; instead, it appeals to buyers who need the practicality of a wagon but refuse to compromise on the premium driving experience expected from a Mercedes-Benz.

City and highway performance

The E450 All-Terrain delivers 21 MPG in the city and 28 MPG on the highway. The city fuel economy reflects the stop-and-go nature of urban driving, where the weight of the vehicle and the demands of frequent acceleration affect the numbers. The highway figure is better, showcasing the efficiency of the 3.0L turbocharged inline-six engine and smooth-shifting 9-speed automatic transmission when cruising at steady speeds. The 4Matic all-wheel drive system, essential for many buyers in colder climates, likely has a small impact on these figures compared to a rear-wheel drive configuration, but it is a worthwhile tradeoff for the added security and traction it provides.

Annual fuel cost

According to the EPA estimates, the annual fuel cost for the 2022 Mercedes-Benz E450 4matic All-Terrain is $2,400. This calculation is based on driving 15,000 miles per year and assumes fuel prices consistent with national averages. The actual cost you incur may be higher or lower depending on several factors: your driving style, the type of fuel you purchase (premium fuel is recommended), and where you live. Fluctuations in gasoline prices can also significantly alter the annual cost of ownership. Buyers who frequently exceed 15,000 miles per year, or who live in areas with higher fuel costs, should anticipate spending more.

Real-world expectations

While the EPA estimates provide a useful baseline, real-world fuel economy can vary depending on driving habits and conditions. Owners who frequently drive aggressively or tow heavy loads may find their MPG figures falling below the official estimates. Conversely, those who prioritize smooth acceleration and maintain consistent speeds on the highway could potentially exceed the EPA numbers. It’s also important to recognize the impact of cold weather on fuel economy. Lower temperatures can reduce efficiency, particularly during short trips when the engine hasn’t fully warmed up. To get a sense of real-world owner experiences, consult online forums and owner reviews to understand the spectrum of MPG figures reported by other E450 All-Terrain drivers.

How it compares

Compared to other luxury wagons and SUVs, the E450 All-Terrain’s fuel economy is competitive, but not class-leading. The Volvo V90 Cross Country, another popular wagon with standard all-wheel drive, achieves around 25 MPG combined with its B6 engine, offering slightly better fuel economy versus superior performance. Crossover SUVs like the BMW X3 xDrive30i, with its smaller turbocharged four-cylinder engine, manages closer to 24 MPG combined, effectively matching the Mercedes. But stepping up to the X3 M40i drops that figure significantly. For those considering larger SUVs with three rows, the Acura MDX with SH-AWD returns about 21 MPG combined. These comparisons matter to E450 buyers, who often cross-shop these vehicles and weigh fuel efficiency against other key factors, such as cargo space and luxury amenities. Finding all Mercedes Benz fuel economy data can help inform this decision.

Tips to maximize efficiency

Use the “Comfort” driving mode as the default setting for everyday driving. This mode optimizes the engine and transmission settings for efficiency, prioritizing smooth acceleration and early upshifts. While “Sport” mode offers a more engaging driving experience, it also consumes more fuel due to the more aggressive throttle response and higher engine RPMs.

Maintain proper tire inflation. Underinflated tires increase rolling resistance, which can negatively impact fuel economy. Check your tire pressure regularly and inflate them to the recommended levels, which are typically found on a sticker inside the driver’s side doorjamb. This simple step can contribute to a noticeable improvement in MPG over time.

Avoid unnecessary idling. Idling consumes fuel without covering any distance. If you anticipate being stopped for more than a minute or two, it’s generally more efficient to turn off the engine. Modern engine start-stop systems are designed to automatically shut off the engine at stoplights and restart it , reducing fuel consumption in city driving. It is also worth exploring E450 MPG across all years to see if the start-stop system has improved.

Minimize aggressive driving habits. Rapid acceleration and hard braking consume significantly more fuel than smooth, gradual inputs. Anticipate traffic conditions and maintain a consistent speed whenever possible. Using cruise control on the highway can also help to optimize fuel economy by maintaining a steady speed and minimizing unnecessary acceleration.

Remove unnecessary weight from the vehicle. Carrying excess weight in the cargo area or rear seats can reduce fuel economy. Check the vehicle regularly and remove any items that aren’t needed for the current trip. Even small amounts of weight can add up over time and impact MPG.