The 2019 Mercedes-Benz AMG S65 doesn’t exactly brag about 16 MPG combined. That’s because this isn’t an economy car disguised as a luxury sedan; it’s a clear declaration of power and opulence, propelled by a hand-built 6.0L V12 engine. The person buying this car probably isn’t prioritizing fuel efficiency. Instead, they seek speed, exclusivity, and smooth power delivery. For that, 16 MPG is an accepted compromise.

City and highway performance

EPA estimates of 13 MPG in the city and 22 MPG on the highway show a predictably wide gap. The S65’s strong torque allows for easy acceleration at any speed, meaning even city driving won’t require much engine strain. On the open road, especially at higher speeds, the 7-speed automatic transmission’s long gearing lets the V12 run at lower RPMs, helping achieve the relatively respectable highway number. However, aggressive acceleration and hard driving, even on the highway, will quickly lower that number. Those large turbos need fuel to generate boost.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2019 AMG S65 at $3,600. This is based on driving 15,000 miles per year, with 55% in the city and 45% on the highway, using EPA estimates and national average fuel prices when calculated. Many S65 owners will likely spend more since they may be tempted to exploit the car’s performance. Spirited driving will guarantee lower MPG. The car also requires premium fuel, raising ownership costs. If you’re considering other Mercedes-Benz options, check all Mercedes Benz fuel economy data for comparison.

Real-world expectations

While the EPA figures offer a starting point, the AMG S65’s real-world fuel economy depends heavily on driving style. Gentle cruising can approach the EPA highway estimate, but even moderate turbo use will have a big impact. Expect the combined MPG to drop below 16 if you often push the car to its limits. Colder temperatures and winter fuel blends can also reduce fuel economy, especially on short trips before the engine warms up.

How it compares

The AMG S65 is in a unique category. Its direct rivals are other ultra-luxury sedans, none of which are very economical. The BMW M760i xDrive, with its twin-turbo V12, gets a similar 16 MPG combined, matching the S65’s blend of performance and fuel consumption. The Bentley Flying Spur V8 achieves 15 MPG combined, while offering a different, perhaps even more opulent, version of the ultra-luxury sedan. Even a “lesser” S-Class, like the AMG S63 with its V8, doesn’t necessarily improve dramatically; it’s rated near 19 MPG combined. Those with AMG interest might research AMG MPG across all years. The S65 buyer is buying more than just transportation. Fuel economy is a secondary concern.

Tips to maximize efficiency

While fuel economy isn’t usually important to an AMG S65 owner, some adjustments can help improve it without losing too much driving enjoyment. Avoid quick acceleration and hard braking, as these heavily impact fuel consumption. Use the car’s ECO driving mode when possible, which reduces throttle response and changes transmission settings for better fuel efficiency.

Keep the car properly maintained, with regular tire pressure checks and servicing. Underinflated tires increase rolling resistance, reducing fuel economy. Regular maintenance ensures the engine runs efficiently and that no mechanical problems increase fuel usage.

Keep idling to a minimum. Modern engines consume fuel when stopped, so avoid unnecessary idling, especially in traffic or while waiting. Turn off the engine if you’ll be stopped for more than a minute.

Plan routes to avoid congestion and stop-and-go traffic. Constant highway driving is more fuel-efficient than crowded city streets. Navigation systems with real-time traffic updates can help find efficient routes.