26 MPG combined is not the main reason someone buys the 2024 Mercedes-Benz CLE450 4matic coupe. This is a car for aesthetic enjoyment, for the confident presentation of taste. The turbocharged inline-six engine and standard all-wheel drive are there to deliver effortless performance, not to win hypermiling competitions. Nevertheless, this figure represents a reasonable compromise between driving pleasure and fuel consumption for a vehicle in its class.

City and highway performance

The CLE450 4matic achieves an EPA-estimated 23 MPG in city driving and 33 MPG on the highway. The city figure reflects the realities of stop-and-go traffic and frequent acceleration. The engine’s smooth power delivery is appreciated in these conditions, even if it impacts fuel efficiency. The highway figure is more impressive, showcasing the benefits of the nine-speed automatic transmission and the engine’s ability to cruise comfortably at higher speeds. Drivers who frequently take long road trips will find the CLE450 a pleasant and relatively efficient companion, provided they resist the urge to fully exploit the engine’s potential.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2024 Mercedes-Benz CLE450 4matic at $2,250. This figure is based on driving 15,000 miles per year and using national average fuel prices. Individual fuel costs will vary depending on driving habits, local fuel prices, and the type of fuel used. The CLE450 requires premium fuel, which is typically more expensive than regular gasoline, so keep that in mind. While $2,250 annually may be higher than more fuel-efficient vehicles, the CLE450 buyer is likely less sensitive to fuel costs than someone shopping for a more budget-oriented car. For a complete picture of Mercedes Benz fuel economy data, we have you covered here.

Real-world expectations

While the EPA estimates provide a useful baseline, real-world fuel economy will always vary depending on driving style and conditions. Aggressive acceleration, frequent hard braking, and extended idling will all negatively impact fuel consumption. Conversely, smooth and consistent driving, combined with careful anticipation of traffic conditions, can help drivers achieve fuel economy closer to the EPA estimates, or even slightly exceed them. Altitude can also affect MPG. The best way to know what you might get is to track fuel economy on a test drive over your normal routes. See all the CLE450 MPG across all years.

How it compares

The BMW 440i xDrive Coupe, a direct competitor to the CLE450, achieves an EPA-estimated 25 MPG combined. While seemingly close, the BMW has a slightly lower highway rating of 32 MPG. The Audi S5 Coupe achieves 24 MPG combined. Buyers in this segment often cross-shop these vehicles, and while fuel economy isn’t the primary deciding factor, a difference of a few MPG can be a tie-breaker for some. A Porsche 718 Cayman, for example, offers a more focused driving experience but delivers significantly worse fuel economy at 21 MPG combined. The CLE450 offers a good balance of performance, luxury, and reasonable fuel economy for the target buyer.

Tips to maximize efficiency

Use the CLE450’s driving modes. The “Eco” mode optimizes engine and transmission settings for maximum fuel efficiency. While it may make the car feel slightly less responsive, it can make a noticeable difference in fuel consumption, especially during city driving. Experiment with this mode to see if the tradeoff between performance and efficiency is acceptable for your daily commute.

Pay close attention to tire pressure. Underinflated tires increase rolling resistance, which reduces fuel economy. Check your tire pressure regularly and maintain it at the recommended level, which can be found on a sticker inside the driver’s side doorjamb. By keeping tires properly inflated you’re not only improving fuel economy, but extending the life of your tires.

Avoid unnecessary acceleration. The CLE450’s turbocharged engine delivers plenty of power, but using it frequently will take a toll on fuel economy. Drive smoothly and gradually increase speed. Anticipate traffic conditions and avoid sudden braking whenever possible. Smoother driving is safer and improves fuel economy.

Minimize idling. Idling consumes fuel without covering any distance. If you’re stopped for more than a minute or two, turn off the engine. Modern cars are designed to restart quickly and efficiently, so there’s no need to keep the engine running unnecessarily. Even short periods of idling can add up over time and significantly reduce fuel economy.