For a buyer of the 2023 Mercedes-Benz S580e 4matic, the 23 MPG combined rating is likely not a primary concern. This car is not about maximizing fuel savings, but about a smooth blend of opulent luxury, cutting-edge technology, and surprising efficiency for a supremely comfortable, technologically advanced flagship sedan with a plug-in hybrid powertrain.

City and highway performance

The EPA estimates the S580e gets 20 MPG in the city and 29 MPG on the highway. These figures don’t tell the whole story. The electric motor provides a significant boost, especially in cities, allowing for potentially higher MPG if you prioritize electric-only driving. On the open road, the smooth and powerful 3.0-liter inline-six engine effortlessly moves the S580e, returning respectable fuel economy for a vehicle of its size and power, especially with regenerative braking.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2023 Mercedes-Benz S580e is $2,500. This is based on driving 15,000 miles per year, with 55% in the city and 45% on the highway. It also assumes national average fuel prices. Your actual fuel costs may vary depending on your driving habits, local gas prices, and how much you use the car’s plug-in hybrid capabilities.

Real-world expectations

Achieving the EPA’s combined 23 MPG rating depends heavily on how you use the S580e’s plug-in hybrid system. Frequent charging and prioritizing electric driving, especially for shorter trips, will significantly increase your fuel economy. But relying solely on the gasoline engine will lead to lower MPG. Expect something in the mid-20s for combined MPG in mixed driving, with the potential to exceed 30 MPG on longer highway trips when driven conservatively. City driving can see numbers far exceed the rated 20 MPG when using the electric motor.

How it compares

The S580e’s competitor set is small, but benchmarking is important. The non-hybrid BMW 740i achieves a combined 28 MPG, potentially offering better fuel economy if you don’t use the S580e’s electric capabilities. The Audi A8, with its standard mild-hybrid system, gets around 22 MPG combined, making the S580e potentially more efficient. Even among ultra-luxury vehicles, efficiency varies. The plug-in hybrid system gives the S580e an advantage, but it’s up to the driver to capitalize on it. For access to all Mercedes Benz fuel economy data, click here.

Tips to maximize efficiency

Consistently charge the S580e’s battery to maximize your fuel economy. Plug it in whenever possible, like you would your phone. This will allow you to maximize the use of the electric motor, especially for short trips, reducing how much gas you use.

Use the car’s driving modes. The “Electric” mode prioritizes electric-only driving until the battery is depleted, while the “Hybrid” mode automatically manages the powertrain for optimal efficiency. Experiment with these modes to see which best suits your driving conditions. Learn more on our page dedicated to S580E MPG across all years.

Practice smooth and gradual acceleration and braking. This allows the regenerative braking system to capture more energy, replenishing the battery and reducing fuel consumption. Avoid aggressive driving habits like sudden acceleration or hard braking, as these will negatively impact your fuel economy.

Plan your routes strategically. Selecting routes that avoid stop-and-go traffic and prioritize smoother, free-flowing roads can improve your fuel economy, especially when driving in electric mode. Use the car’s navigation system to find the most efficient routes.

Keep your tires properly inflated. Underinflated tires increase rolling resistance, which reduces fuel economy. Regularly check your tire pressure and inflate them to the recommended levels. This simple step can translate to fuel savings.