22 MPG combined is the price for those seeking a luxury sports sedan. It blends reliability, understated style, and a naturally aspirated V6 soundtrack in a now-rare all-wheel-drive configuration. The 2023 Lexus IS 350 AWD isn’t about chasing ultimate efficiency numbers. It’s about delivering a specific driving experience that resonates with a particular kind of buyer who prioritizes smoothness and responsiveness over saving fuel.

City and highway performance

The EPA estimates 19 MPG in the city and 26 MPG on the highway for the 2023 Lexus IS 350 AWD. These numbers are a direct result of the engine’s tuning and the needs of all-wheel drive. In urban settings, the engine’s naturally aspirated design means it needs to work a little harder to get going, especially compared to turbocharged competitors that offer low-end torque on demand.

On the highway, the 6-speed automatic transmission does its best to keep the engine in its sweet spot, balancing performance and efficiency for long-distance cruising. Compared to modern 8 or 10-speed transmissions, the older 6-speed means that the IS spends more time in its lower gears, hurting its highway economy. Still, the powertrain provides a satisfying, linear power delivery that many enthusiasts prefer.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2023 Lexus IS 350 AWD is $2,650. This is calculated based on driving 15,000 miles per year and using national average fuel prices. Your actual fuel costs will vary depending on your driving habits, the type of driving you do (city vs. highway), and the local price of gasoline. Buyers drawn to the IS 350 AWD appreciate the car’s reliable engineering and aren’t typically deterred by slightly higher running costs in exchange for the performance and reliability Lexus is known for.

Real-world expectations

The EPA provides a standardized estimate, but real-world MPG for the 2023 Lexus IS 350 AWD will vary depending on driving style and conditions. Aggressive acceleration, frequent hard braking, and extended idling will significantly reduce fuel economy.

Drivers who adopt a smoother, more conservative driving style and prioritize steady highway speeds can expect to get closer to the EPA’s highway estimate, perhaps even exceeding it slightly. Terrain also plays a role. Hilly or mountainous areas will naturally reduce MPG figures.

How it compares

The fuel economy of the IS 350 AWD must be considered when compared to its rivals. The BMW M340i xDrive, with its turbocharged inline-6, manages a combined 26 MPG. The Mercedes-Benz C300 4MATIC, with its turbocharged 4-cylinder engine, achieves around 28 MPG combined. The Acura TLX SH-AWD manages 24 MPG combined.

Buyers considering the IS 350 AWD are often willing to sacrifice some MPG for the feel of the naturally aspirated V6 and the reputation for longevity associated with Lexus vehicles. You can see IS MPG across all years here. These buyers also may be trading a few MPG for Lexus’ reputation regarding build quality and reliability, as well as the smoothness of the brand’s V6 engines.

Tips to maximize efficiency

Avoid aggressive acceleration and hard braking to conserve fuel. The IS 350 AWD responds best to smooth, deliberate inputs. Anticipate traffic flow and maintain a steady speed whenever possible to minimize unnecessary fuel consumption.

Ensure your tires are properly inflated. Underinflated tires increase rolling resistance, which can negatively impact fuel economy. Check your tire pressures regularly and maintain the recommended levels specified on the vehicle’s doorjamb sticker.

Reduce unnecessary weight by removing any extra items in the trunk or backseat. This added weight to the vehicle requires more energy to accelerate and maintain speed. Remove any unnecessary items to improve fuel efficiency.

Consider using the “Eco” drive mode when appropriate. While it may slightly reduce throttle response and power output, it can help optimize fuel consumption, especially during city driving or steady highway cruising. Using Eco mode all the time can blunt the driving experience that the IS 350’s target buyers seek.

Keep your vehicle properly maintained with regular oil changes, air filter replacements, and spark plug inspections. This ensures that your engine is running efficiently. Neglecting maintenance can lead to reduced fuel economy and potential engine problems. For all Lexus fuel economy data, see our Lexus brand page.