21 MPG combined might raise eyebrows, but it reflects the 2022 Lexus LS 500 AWD’s priorities. The car isn’t designed to sip fuel. It’s a flagship luxury sedan engineered for effortless power, quiet comfort, and all-weather confidence. Its buyers value refinement and a smooth driving experience above all else.

City and highway performance

The EPA estimates the LS 500 AWD achieves 17 MPG in the city and 27 MPG on the highway. The city number reflects stop-and-go traffic, where the 3.4L twin-turbo V6 engine works harder because of the car’s weight. The highway number is better, as the 10-speed automatic transmission allows the engine to cruise at low RPMs, maximizing fuel efficiency on long trips. Considering the LS 500 prioritizes comfort and quietness, that highway MPG is important for cross-country trips. This transmission reacts quickly to driving situations yet doesn’t call attention to itself.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2022 Lexus LS 500 AWD at $2,750. This figure is based on driving 15,000 miles per year and average national fuel prices. The actual cost will vary depending on driving habits, local fuel prices, and the type of fuel used. It’s a realistic estimate of the ongoing expense of owning this luxury sedan.

Real-world expectations

While the EPA estimates provide a baseline, real-world fuel economy often differs. Aggressive driving, frequent short trips, and cold weather can all negatively impact the LS 500’s MPG. Careful driving, consistent highway speeds, and regular maintenance can improve it. Experience shows that the LS 500 AWD is likely to deliver fuel economy within a few MPGs of the EPA estimates for drivers who adopt a relaxed driving style. Owners should also remember that this isn’t a hybrid, and efficiency will never be its defining feature, but instead a byproduct of its advanced engineering.

How it compares

In the realm of large luxury sedans with all-wheel drive, the LS 500 AWD fits into a specific efficiency niche. The Mercedes-Benz S 500 4MATIC achieves an EPA-estimated 21 MPG combined, mirroring the LS 500. The BMW 740i xDrive lands at 24 MPG combined. These vehicles are fairly comparable, with the choice between each model coming down to styling preferences more than fuel economy. If you’re looking for better MPGs, you might consider the Lexus ES 300h, which offers hybrid efficiency, but lacks the LS’s prestige and rear-seat legroom. Explore all Lexus fuel economy data to evaluate other options within the Lexus brand, or review LS MPG across all years.

Tips to maximize efficiency

Adopt a gentle driving style. The LS 500’s twin-turbo V6 offers plenty of torque at low RPMs, so there’s rarely a need to accelerate aggressively. Gradual acceleration and smooth braking will both improve fuel economy.

Maintain proper tire inflation. Underinflated tires increase rolling resistance, which reduces fuel efficiency. Check your tire pressure regularly and inflate them to the recommended level, typically found on a sticker inside the driver’s side doorframe.

Minimize idling. Letting the engine idle wastes fuel. If you’re stopped for more than a minute or two, turn off the engine. The LS 500’s engine restarts quickly and smoothly, thanks to its advanced starter motor.

Use cruise control on the highway. Cruise control helps maintain a consistent speed, which reduces unnecessary acceleration and braking and can significantly improve fuel economy on long highway trips. Take advantage of this feature, especially on long-distance drives that this sedan makes exceptionally comfortable.