The 2022 Infiniti QX50 AWD with the 2.0L 4-cylinder engine gets 25 MPG combined, which is acceptable but not amazing. This vehicle isn’t trying to match a Prius for fuel efficiency. It provides a comfortable, stylish, and technologically advanced experience for buyers who value those things more than squeezing every last mile from a gallon of premium fuel.

City and highway performance

The EPA estimates of 22 MPG in the city and 28 MPG on the highway reflect the QX50’s powertrain performance. The innovative variable compression engine requires some effort to reach peak efficiency. City driving, with its frequent stops, prevents the engine from settling into its most efficient compression ratio. On the highway, however, the engine can cruise more consistently, leading to better fuel economy.

That 28 MPG is achievable on long road trips if you avoid hard acceleration.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2022 Infiniti QX50 AWD at $2,300. This is based on driving 15,000 miles per year and using the national average fuel price at the time of calculation. This is a helpful starting point, but your actual costs will vary based on your driving, the fuel you use (premium is recommended), and local fuel prices.

If you drive significantly more than 15,000 miles per year, or fuel is more expensive in your area, you’ll likely spend more.

Real-world expectations

While the EPA numbers are a good reference, it’s important to manage your expectations. Drivers who often drive aggressively or in heavy traffic probably won’t consistently get 25 MPG. But drivers who focus on fuel-efficient driving, like keeping a steady speed and avoiding quick acceleration, might do better than the EPA estimate.

Check your trip computer’s fuel economy display to better understand your QX50’s fuel consumption in your specific driving conditions. All all Infiniti fuel economy data is based on these estimates, which may need adjustments based on the data you collect.

How it compares

The QX50’s fuel economy is competitive, but not the best. The Acura RDX, for example, gets about 23 MPG combined with its standard AWD. The Lexus NX 350h hybrid achieves a much better 39 MPG combined. The BMW X3 xDrive30i gets around 24 MPG combined. These MPG differences are important to buyers comparing brands, but for the QX50 customer, fuel economy is one factor to consider, not the only one, when compared with QX50 MPG across all years.

Tips to maximize efficiency

The QX50’s variable compression engine responds to driving style. Avoid hard acceleration and braking to allow the engine to stay in its most efficient compression ratio longer.

Make sure your tires are properly inflated. Underinflated tires increase rolling resistance, which hurts fuel economy. Check your tire pressure regularly and inflate them to the recommended pressure listed on the doorjamb sticker.

Reduce extra weight. Carrying extra cargo in the trunk or on the roof rack increases the vehicle’s weight, which lowers fuel economy. Remove any unnecessary items.

Plan your routes. Avoid congested areas and routes with frequent stops and traffic lights. Using a navigation system to find the most efficient route can save fuel and is faster.

Consider using the QX50’s drive mode selector. While “Sport” mode improves performance, it also reduces fuel economy. Use “Eco” or “Standard” mode for everyday driving to save fuel.