| Engine | 5.7L 8-cyl |
| Transmission | Automatic (S6) |
| Drive | Part-time 4-Wheel Drive |
| Fuel Type | Regular Gasoline |
| Vehicle Class | Standard Sport Utility Vehicle 4WD |
| Start-Stop | No |
| EPA Vehicle ID | 43212 |
14 MPG combined is the stark reality for anyone considering a 2021 Toyota Sequoia 4WD with the 5.7L V8. It’s a number that would be a deal-breaker for most car buyers, but the Sequoia isn’t aimed at the average commuter. This vehicle is purpose-built for hauling large families, towing substantial loads, and conquering challenging terrain, and for those buyers, the fuel economy, while undeniably poor, is often a necessary trade-off for its unparalleled capabilities.
City and highway performance
The Sequoia’s EPA estimates break down to 13 MPG in the city and 17 MPG on the highway. The city figure reflects the engine’s thirst during stop-and-go traffic and the vehicle’s considerable weight. On the open road, the 17 MPG is achievable if you maintain a steady cruising speed, though any aggressive acceleration or hilly terrain will quickly diminish it. These numbers are a direct consequence of the Sequoia’s strong V8 engine, its full-time 4WD system, and its truck-based architecture which is designed for durability and towing power rather than efficiency.
Annual fuel cost
According to the EPA, the estimated annual fuel cost for the 2021 Toyota Sequoia 4WD is $3,150. This figure is based on driving 15,000 miles per year, with 55% of those miles driven in the city and 45% on the highway, and using the national average fuel price when the data was compiled. It’s a substantial sum, representing a significant ongoing expense for Sequoia owners. Prospective buyers should carefully consider this cost and factor it into their overall budget before committing to the vehicle.
Real-world expectations
While the EPA estimates provide a baseline, real-world fuel economy for the Sequoia can vary significantly depending on driving habits, road conditions, and the use of four-wheel drive. Aggressive driving, frequent towing, and operating the vehicle in challenging off-road conditions will undoubtedly lower the MPG. Conversely, gentle acceleration, careful highway cruising, and minimizing four-wheel drive usage can potentially improve fuel economy, though likely not by a substantial margin. Owners consistently report numbers that hover around the EPA estimates, with slight variations based on their individual circumstances.
How it compares
The Sequoia’s fuel economy lags behind many of its competitors in the full-size SUV segment. A Ford Expedition with the EcoBoost engine, for example, can achieve up to 20 MPG combined in 4×4 configuration. The Chevrolet Tahoe with its 5.3L V8 manages around 17 MPG combined. Even the Nissan Armada, another V8-powered SUV, often sees slightly better real-world results. This comparison matters because while the Sequoia excels in reliability and resale value, its fuel consumption is a clear disadvantage, particularly for buyers who prioritize fuel efficiency. Comparing SEQUOIA MPG across all years reveals this has long been the truck’s weakness. For those considering other Toyota options, you can explore all Toyota fuel economy data here.
Tips to maximize efficiency
Regular maintenance is key. Ensure your Sequoia’s tires are properly inflated, as underinflated tires increase rolling resistance and reduce fuel economy. A properly tuned engine and clean air filter are equally important for optimal combustion and efficiency.
Minimize idling time. The Sequoia’s large V8 consumes a significant amount of fuel when idling. If you anticipate a wait of more than 30 seconds, it’s generally more fuel-efficient to turn off the engine and restart it when you’re ready to go.
Avoid aggressive driving habits. Rapid acceleration and hard braking waste fuel. Maintain a smooth and consistent speed whenever possible. Using cruise control on the highway can also help maintain a steady pace and improve fuel economy.
Consider the weight you’re carrying. The Sequoia is capable of hauling a lot, but extra weight increases fuel consumption. Remove any unnecessary items from the vehicle to reduce the load on the engine.
Use four-wheel drive only when necessary. Engaging four-wheel drive increases the vehicle’s drivetrain loss and reduces fuel economy. Disengage it when driving on paved roads to maximize efficiency.