Lexus · 2021
LS 500h AWD 3.5L 6-cyl
✓ EPA Verified
Premium Gasoline
Midsize Cars
All-Wheel Drive
City
23
MPG
Combined
26
MPG
Highway
29
MPG
Annual Fuel Cost
$2,250
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$100
more per year
Class Comparison — Midsize Cars
Bottom 42%
Better than 42 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 26 MPG
This vehicle
26 MPG
Class average
35 MPG
Class lowest
13 MPG
EPA Energy & Environment Scores
5
Energy Score
Out of 10
5
GHG Score
Out of 10
343 lbs
Annual CO₂
g/mile tailpipe CO₂
Yes
Start-Stop
Auto stop-start
Vehicle Specifications
Engine3.5L 6-cyl
TransmissionAutomatic (AV-S10)
DriveAll-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassMidsize Cars
TrimHybrid
Engine DescSIDI & PFI; Hybrid
Start-StopYes
EPA Vehicle ID43743

26 MPG combined isn’t going to win any hypermiling contests, but it’s an acceptable figure for the 2021 Lexus LS 500h AWD, a flagship luxury sedan designed to prioritize a quiet and effortless power over outright fuel efficiency. This is a car for executives who value a whisper-quiet cabin, all-weather confidence, and the subtle nod to less gas provided by its hybrid powertrain, even if it doesn’t dramatically cut fuel costs compared to its competitors.

City and highway performance

The LS 500h’s EPA ratings break down to 23 MPG in the city and 29 MPG on the highway. The city figure reflects the hybrid system’s ability to use electric power at lower speeds, improving efficiency during stop-and-go driving. The highway number, while a step up, indicates that at higher speeds, the gasoline engine becomes more dominant. Keep in mind that these are EPA estimates, obtained under controlled conditions; your individual mileage will vary based on driving style, traffic, and terrain.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2021 Lexus LS 500h AWD at $2,250. This figure is based on driving 15,000 miles per year and using national average fuel prices. While not exorbitant for a car in this class, it’s a worthwhile consideration for buyers who drive significantly more than average or who live in areas with particularly high fuel costs. Buyers considering a six-figure luxury sedan are generally less sensitive to fluctuations in fuel prices than those shopping for budget-oriented vehicles.

Real-world expectations

Drivers often experience a range of fuel economy in the real world, which varies based on individual driving habits and environmental conditions, despite the EPA estimates. Aggressive acceleration will certainly dip below the EPA combined figure, while a gentler, more deliberate approach could nudge it slightly higher, especially in city driving. Remember, the LS 500h is a large, comfortable sedan, and its hybrid powertrain isn’t designed to be pushed hard; smooth, consistent throttle inputs are key to maximizing its efficiency. See LS MPG across all years.

How it compares

Fuel economy is a relative game, and the LS 500h exists in a segment where outright efficiency isn’t always the top priority. The non-hybrid LS 500, for example, achieves a combined EPA rating of around 21 MPG, making the 500h a tangible improvement. Comparing it to other hybrid luxury sedans reveals a mixed bag. The BMW 745e xDrive plug-in hybrid, when running in hybrid mode after the electric range is depleted, posts similar numbers to the LS 500h. However, the Mercedes-Benz S560e, a previous-generation plug-in hybrid, offered comparable MPG but has been replaced with newer, all-electric models. While the LS 500h holds its own, the shift toward electrification across the luxury segment means more plug-in hybrid and all-electric alternatives are emerging, offering possibilities for even greater fuel efficiency. Be sure to explore all Lexus fuel economy data.

Tips to maximize efficiency

Use the LS 500h’s ECO drive mode. This setting adjusts throttle response and climate control settings to prioritize fuel conservation. It’s particularly effective in minimizing fuel consumption during daily commuting.

Practice smooth and steady acceleration. The hybrid system works best when it isn’t constantly forced to call upon the gasoline engine for sudden bursts of power. Anticipate traffic flow and accelerate gradually to maintain momentum.

Minimize excessive idling. While the hybrid system will shut off the engine at a standstill, prolonged idling still consumes fuel. If you anticipate a long wait, consider turning off the vehicle completely. Restarting the hybrid powertrain is smooth and far more efficient than letting it idle.

Ensure your tires are properly inflated. Underinflated tires increase rolling resistance and negatively impact fuel economy. Check your tire pressure regularly and inflate them to the recommended pressure listed on the driver’s side doorjamb.

Regular maintenance is critical. Keeping the engine properly tuned and ensuring all components are functioning optimally is essential for maximizing fuel efficiency. Adhere to the manufacturer’s recommended maintenance schedule for oil changes, air filter replacements, and other services specific to hybrid powertrains.