27 MPG combined positions the 2021 Audi A4 S line quattro as respectable, though not groundbreaking, when it comes to fuel efficiency. More importantly, it’s a reasonable compromise for buyers who prioritize driving dynamics, all-weather grip, and a premium interior over lower fuel costs. This isn’t a hybrid chasing maximum mileage; it’s a sporting sedan designed to deliver confident performance in varied conditions, and that informs its fuel economy.

City and highway performance

The EPA estimates for the A4 S line quattro break down to 24 MPG in the city and 31 MPG on the highway. These figures reflect the realities of stop-and-go traffic versus steady-state cruising. The city MPG is adequate, suggesting the engine’s stop/start system and efficient tuning are making a difference. The highway number, while not class-leading, demonstrates that the A4 S line quattro can be a comfortable and relatively frugal long-distance companion. The 7-speed automatic transmission helps keep the engine in its optimal rev range, contributing to efficiency on the open road.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2021 Audi A4 S line quattro at exactly $2,150. This figure is based on driving 15,000 miles per year and using national average fuel prices. It’s a standardized calculation intended to provide a consistent benchmark for comparison across different vehicles. Keep in mind that your actual fuel costs may vary depending on your driving habits, local fuel prices, and the type of fuel you use (premium is recommended for optimal performance).

Real-world expectations

The EPA provides a standardized rating, but real-world fuel economy will inevitably vary. Aggressive driving, frequent short trips, and extreme weather conditions can all negatively impact MPG. Conversely, careful driving habits, regular maintenance, and optimal tire inflation can help you achieve or even exceed the EPA estimates.

Many drivers report figures close to the EPA numbers, suggesting they are a reasonable representation of what to expect with mixed driving. Drivers who prioritize a smooth, steady driving style will likely see the most favorable results.

How it compares

The A4 S line quattro occupies a competitive space within the luxury sedan segment. The BMW 330i xDrive, a direct rival, achieves a similar 28 MPG combined. The Mercedes-Benz C300 4MATIC posts around 26 MPG combined. Acura’s TLX SH-AWD also lands in the same ballpark. While specific trims and options can influence these numbers, the A4 S line quattro is neither the most nor the least efficient in its class.

Buyers drawn to the A4’s blend of style, technology, and quattro all-wheel drive understand that they’re accepting a slight compromise in fuel economy compared to, say, a Lexus ES 350, which prioritizes efficiency above all else.

Tips to maximize efficiency

The A4 S line quattro responds well to smooth, progressive acceleration. Avoid abrupt starts and stops, as these actions consume significantly more fuel. Anticipate traffic flow and maintain a consistent speed whenever possible. This car is not designed to be floored at every green light.

Ensure your tires are properly inflated to the recommended pressure, which is typically found on a sticker inside the driver’s side doorjamb. Underinflated tires increase rolling resistance and reduce fuel economy. Check tire pressure regularly, especially with changes in temperature.

Regular maintenance, including oil changes and air filter replacements, is critical for maintaining optimal fuel efficiency. A well-maintained engine runs more smoothly and efficiently, leading to better mileage. Consult your owner’s manual for the recommended maintenance schedule.

Lighten your load. Excess weight in the vehicle can negatively impact fuel economy. Remove any unnecessary items from the trunk and cabin. Even small amounts of extra weight add up over time.

Consider using the Audi Drive Select system’s “Efficiency” mode, if equipped. This mode optimizes various vehicle settings, such as throttle response and transmission shift points, to prioritize fuel economy. While it may slightly diminish performance, it can noticeably improve MPG in certain driving conditions.

Find all Audi fuel economy data here. We also provide A4 MPG across all years.