Mercedes-Benz · 2019
CLS450 3.0L 6-cyl
✓ EPA Verified
Premium Gasoline
Compact Cars
Rear-Wheel Drive
City
24
MPG
Combined
26
MPG
Highway
31
MPG
Annual Fuel Cost
$2,250
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$100
more per year
Class Comparison — Compact Cars
Bottom 41%
Better than 41 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 26 MPG
This vehicle
26 MPG
Class average
33 MPG
Class lowest
12 MPG
EPA Energy & Environment Scores
5
Energy Score
Out of 10
5
GHG Score
Out of 10
334 lbs
Annual CO₂
g/mile tailpipe CO₂
Yes
Start-Stop
Auto stop-start
Vehicle Specifications
Engine3.0L 6-cyl
TransmissionAutomatic 9-spd
DriveRear-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassCompact Cars
TrimHybrid
Engine DescSIDI; Mild Hybrid
Start-StopYes
EPA Vehicle ID40934

The 2019 Mercedes-Benz CLS450, with its 3.0L inline-six, gets a combined fuel economy of 26 MPG. While not the most fuel-efficient in its class, it’s a respectable figure for a stylish, powerful four-door coupe that prioritizes driving pleasure and luxury. This car appeals to image-conscious professionals, empty nesters, and anyone who appreciates a finely crafted vehicle. They understand that some fuel consumption comes with the territory.

City and highway performance

The EPA estimates the CLS450 gets 24 MPG in the city and 31 MPG on the highway. The city number reflects the stop-and-go driving that many CLS450 owners will experience during their daily commutes. The potent 362-horsepower engine, using Mercedes’ EQ Boost mild-hybrid system, provides ample low-end torque for effortless acceleration from a standstill. The highway figure is more impressive, showcasing the efficiency of the nine-speed automatic transmission and the engine’s ability to cruise comfortably at higher speeds. The CLS450 is a supremely comfortable long-distance cruiser, and the 31 MPG makes extended road trips more palatable.

Annual fuel cost

According to the EPA, the estimated annual fuel cost for the 2019 Mercedes-Benz CLS450 is $2,250. This is based on driving 15,000 miles per year and using national average fuel prices. Keep in mind that fuel prices fluctuate, and your personal driving habits will ultimately determine your actual fuel expenses. Someone who primarily drives in the city or accelerates quickly will likely exceed this estimate, while someone who does mostly highway driving and practices efficient driving techniques could potentially see a lower annual cost.

Real-world expectations

While the EPA provides a standardized test, real-world fuel economy can vary based on many factors. Driving style is a primary factor, as aggressive acceleration and hard braking significantly impact fuel consumption. Traffic conditions, weather, and even tire pressure play a role. Expect the lower end of the EPA range if you frequently encounter heavy traffic or prioritize performance. However, with mindful driving and optimized tire pressure, achieving or even slightly exceeding the EPA highway figure is certainly possible. Browse CLS450 MPG across all years to see what other owners are reporting.

How it compares

The CLS450 is in a competitive segment, and fuel economy can set models apart. The BMW 540i, another stylish and performance-oriented sedan, gets a similar 25 MPG combined. The Audi A7, a comparable four-door coupe, also posts around 25 MPG combined with its six-cylinder engine. The Porsche Panamera, with its base engine, sees similar numbers as well. The all-electric Tesla Model S is very different, with zero tailpipe emissions and no need for gasoline. However, the Tesla appeals to a different buyer, one who is willing to embrace EVs. Buyers considering the CLS450 value its combination of style, performance, and luxury, and are generally willing to accept its fuel economy as a trade-off. View all Mercedes Benz fuel economy data for comparison against other models in the lineup.

Tips to maximize efficiency

Use the CLS450’s drive modes. Selecting “Comfort” or “Eco” mode will optimize the engine and transmission settings for fuel efficiency. These modes typically soften throttle response and encourage earlier upshifts, promoting smoother and more economical driving.

Monitor your tire pressure regularly. Underinflated tires increase rolling resistance, which forces the engine to work harder and consume more fuel. Check your owner’s manual for the recommended tire pressure and maintain it consistently.

Avoid aggressive driving habits. Rapid acceleration, hard braking, and excessive speeding increases fuel consumption. Practicing smooth and consistent driving techniques will significantly improve your MPG.

Reduce unnecessary weight. Carrying extra cargo adds weight to the vehicle, which requires more energy to accelerate and maintain speed. Remove any items from the trunk or cabin that you don’t need regularly.

Plan your trips and avoid peak traffic times when possible. Stop-and-go traffic burns fuel, so try to schedule your drives during off-peak hours whenever possible. Use navigation apps to identify alternate routes and avoid congestion.