16 MPG combined is not a misprint. That’s the EPA fuel economy rating for the 2019 Mercedes-Benz AMG S65 Coupe, a vehicle that wasn’t designed to conserve fuel. This is a hand-built, V12-powered example of excess, luxury, and performance. To be clear, nobody shopping for an S65 Coupe is also considering a Prius. They aren’t worried about their carbon footprint. They are buying a statement, an experience, and a very fast way to travel, and they are willing to pay for it.

City and highway performance

That 16 MPG combined rating breaks down to 13 MPG in the city and 21 MPG on the highway. The city figure is predictably poor, reflecting the engine’s thirst for fuel during stop-and-go driving. The highway number, while still not impressive, is at least somewhat respectable. A well-maintained engine, steady speed, and gentle throttle inputs can help you achieve numbers closer to that 21 MPG figure, but aggressive acceleration will quickly diminish any fuel savings.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2019 Mercedes-Benz AMG S65 Coupe at $3,600. This figure is based on driving 15,000 miles per year, with 55% of those miles driven in the city and 45% on the highway, using national average fuel prices. Owners of the S65 Coupe are likely exceeding that 15,000-mile figure and using premium fuel, so the actual cost could be significantly higher. However, fuel cost is not typically a huge concern for those who can afford this car.

Real-world expectations

Forget keeping up with traffic: this car *is* traffic. The S65’s twin-turbo V12 provides significant power, and resisting the urge to use its power is difficult. Achieving the EPA’s 16 MPG combined in real-world driving is ambitious. Expect a figure closer to 14 MPG, especially if you enjoy the engine’s torque and exhaust sound. Remember, even gentle acceleration in this car is faster than most cars at full throttle.

How it compares

Compared to other high-performance luxury coupes, the S65’s fuel economy is predictably poor, but within the expected range. For example, the V8-powered AMG S63 Coupe, while still thirsty, manages a slightly better 19 MPG combined. A BMW M8 Competition Coupe achieves around 17 MPG combined, offering more agile handling. Even the Bentley Continental GT, a similar opulent grand tourer, manages a marginally better 18 MPG combined with its W12 engine. These comparisons matter because even buyers unconcerned about fuel costs still tend to look critically at all data. For all Mercedes Benz fuel economy data, check out this page. And learn more about AMG MPG across all years here on this page.

Tips to maximize efficiency

While focusing on fuel efficiency in an S65 Coupe might seem contrary to its purpose, there are steps you can take to minimize fuel consumption. Smooth acceleration and anticipating traffic can help reduce hard acceleration, a major fuel-consuming activity in any vehicle.

Unlike some cars with “Eco” modes that significantly alter performance, the S65 doesn’t significantly change the engine’s output in its comfort settings. Focus on a light touch, using only as much throttle as needed to maintain speed, and avoid unnecessary acceleration from stoplights.

Regular maintenance is always important. A properly maintained engine will inherently be more efficient. Ensure the car receives regular servicing to maintain performance and fuel economy.

Long, steady highway journeys are where the S65 is most comfortable, and where it can achieve its best fuel economy. Avoid aggressive overtaking and maintain a consistent speed using cruise control to maximize mileage on long drives.