21 MPG combined is not going to impress any Prius owners, but it’s a perfectly acceptable figure for the 2018 Mercedes-Benz S560 4matic Coupe, a car built for sybaritic comfort and effortless performance, not hypermiling. This is a statement piece, a rolling sculpture that coddles its occupants in a cocoon of leather, wood, and technology while delivering prodigious power on demand. The owner who buys this car cares more about the smoothness of the ride and the burble of the V8 than squeezing every last mile from a gallon of premium.

City and highway performance

The EPA estimates the S560 Coupe achieves 17 MPG in the city and 27 MPG on the highway. The city number reflects the engine’s need to work harder in stop-and-go traffic, battling the car’s considerable weight. The highway figure benefits from the nine-speed automatic transmission and the engine’s ability to cruise comfortably at lower RPMs. While 27 MPG might seem decent, remember this figure is achieved under ideal, steady-state conditions. Expect a lower number if you’re frequently exploiting the engine’s considerable horsepower for overtaking or simply enjoying the car’s performance.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2018 Mercedes-Benz S560 4matic Coupe at $2,750. This figure is based on driving 15,000 miles per year and using the national average fuel price for premium gasoline. This is a theoretical number. If you drive fewer miles, your cost would be lower; if you drive more aggressively, your expenses could climb significantly. Given the S560’s target demographic, a few extra dollars at the pump are unlikely to cause sleepless nights. They are more concerned with experiencing the drive.

Real-world expectations

While EPA estimates provide a useful benchmark, real-world fuel economy often deviates. S560 owners should realistically expect to see numbers somewhat below the EPA combined figure, particularly if their driving is primarily urban. However, long highway trips at consistent speeds can approach or even surpass the 27 MPG estimate. Weather conditions and proper tire inflation can also affect MPG. More information about S560 MPG across all years can provide you with an idea of what real owners are reporting.

How it compares

Compared to other high-performance luxury coupes, the S560’s fuel economy is generally in line with expectations. The BMW M850i xDrive Coupe, another similarly powerful and luxurious offering, delivers an EPA-estimated 17 MPG city and 25 MPG highway, a bit less than the S560 on the highway. The Porsche 911 Carrera 4S, while sportier, achieves a slightly better 20 MPG city and 26 MPG highway. Buyers in this rarefied segment understand trade-offs. If they prioritize efficiency above all else, they likely wouldn’t be cross-shopping these vehicles. It’s more about the unique blend of performance, comfort, and prestige each car offers. For a broader view, compare all Mercedes Benz fuel economy data.

Tips to maximize efficiency

Use the “Comfort” driving mode in most situations. This setting optimizes the engine and transmission for efficiency rather than outright performance. Sport and Sport+ modes are enjoyable, but they hold gears longer and use more fuel.

Minimize idling. The S560’s engine consumes fuel even when stationary. Avoid prolonged idling, especially in traffic or when waiting for someone. Activate the ECO start/stop system; this automatically shuts off the engine when the car is stopped.

Maintain proper tire inflation. Underinflated tires increase rolling resistance, which reduces fuel economy. Keep the tires inflated to the recommended pressure listed on the doorjamb sticker.

Avoid aggressive acceleration and braking. Smooth, gradual inputs are more fuel-efficient than abrupt maneuvers. Anticipate traffic flow and maintain a steady pace.

Consider the grade of fuel. Although premium is recommended, using a lower octane fuel will impact performance, and potentially fuel economy. Sticking to the manufacturer’s recommendation will yield better results overall.