18 MPG combined isn’t going to win any fuel economy awards, but it’s a figure largely irrelevant to the buyer targeting a 2018 Mercedes-Benz AMG E63 S 4matic. This isn’t just transportation; it’s a statement. It’s the furious symphony of a hand-built 4.0L biturbo V8 unleashed, wrapped in the (relatively) subtle cloak of a mid-size Mercedes-Benz sedan. Fuel consumption is secondary to raw, unadulterated performance.

City and highway performance

The EPA pegs the 2018 AMG E63 S at 15 MPG in the city and 22 MPG on the highway. These figures reflect the car’s dual nature. The city MPG demonstrates the penalty for lugging around a powerful engine and all-wheel-drive system in stop-and-go traffic. The highway number, while better, still acknowledges the aerodynamic realities of a boxy sedan encountering significant wind resistance at higher speeds. While the nine-speed automatic transmission aids in optimizing fuel efficiency when cruising, it can only do so much against the inherent demands of producing 603 horsepower.

Annual fuel cost

The EPA estimates an annual fuel cost of $3,200 for the 2018 AMG E63 S. This figure is based on driving 15,000 miles per year, with 55% of those miles driven in the city and 45% on the highway. The calculation also uses the national average fuel price for premium unleaded gasoline, which this high-performance engine requires. Buyers will recognize that fuel prices fluctuate, and aggressive driving will certainly inflate this annual cost. However, for those capable of affording a six-figure performance sedan, an extra few hundred (or even thousand) dollars per year in fuel is unlikely to be a significant deterrent.

Real-world expectations

The EPA figures should be considered a best-case scenario. Real-world fuel economy will vary considerably depending on driving style, traffic conditions, and even weather. Drivers who frequently exploit the AMG E63 S’s prodigious power and let’s be honest, who wouldn’t? are likely to see figures significantly lower than the EPA estimates. Those with a lighter foot and a penchant for highway cruising might achieve closer to the advertised numbers. Ultimately, with a vehicle like this, fuel economy is often more of an afterthought than a primary concern.

How it compares

The AMG E63 S competes in a rarefied segment of high-performance luxury sedans where efficiency takes a back seat to power and prestige. The 2018 BMW M5, for instance, achieves a slightly better 17 MPG city and 24 MPG highway, yet that marginal improvement is unlikely to sway a buyer drawn to the specific driving dynamics and aesthetics of the Mercedes-AMG. Similarly, the Porsche Panamera Turbo offers comparable performance with EPA ratings of 18 MPG city and 25 MPG highway. Those considering Audi might look at the RS7, which offers similar performance to the AMG while delivering around 15 city / 25 highway, trading some handling prowess for distinctive styling. Buyers in this segment are typically cross-shopping based on brand loyalty, performance characteristics, and subjective elements like interior design, not solely on MPG. To see AMG MPG across all years, browse our data.

Tips to maximize efficiency

Adopt a smoother driving style. While the AMG E63 S rewards aggressive acceleration, gentle inputs on the throttle and brakes can significantly reduce fuel consumption, especially in city driving. Try to anticipate traffic flow and avoid unnecessary hard stops and starts to conserve fuel.

Use the car’s driving modes. The AMG E63 S offers various driving modes, including “Comfort” or “Eco,” which optimize engine and transmission settings for fuel efficiency. While these modes may temper the car’s performance, they can noticeably improve MPG during daily commutes or long highway drives. Experiment with each mode to determine which best balances performance and efficiency for your driving needs.

Keep your tires properly inflated. Underinflated tires increase rolling resistance, forcing the engine to work harder and burn more fuel. Check your tire pressures regularly and maintain them at the recommended levels, as specified on the door jamb sticker. This is a simple yet effective way to improve your car’s fuel efficiency and extend tire life. For all Mercedes Benz fuel economy data, visit our brand hub.

Minimize idling. Avoid extended periods of idling, as leaving the engine running while stationary consumes fuel without covering any distance. If you’re stopped for more than a minute, turn off the engine to conserve fuel. The AMG E63 S’s rapid restart system ensures a quick and smooth return to operation when you’re ready to go.