22 MPG combined is what you’ll likely get with the 2018 Lexus IS 300 AWD. It’s not a hybrid, and makes no claims of being one. It is a sharp-looking, comfortable sport sedan with all-weather capability and a proven, naturally aspirated V6 engine. The IS 300 AWD delivers a driving experience favored by enthusiasts who prioritize smooth power delivery and confident handling over outright fuel efficiency. It’s a trade-off the typical IS 300 AWD buyer willingly makes.

City and highway performance

The EPA estimates 19 MPG in the city and 26 MPG on the highway for the 2018 Lexus IS 300 AWD. While the highway figure is respectable for a V6-powered AWD sedan, the city MPG reflects the realities of stop-and-go driving with a conventional automatic transmission. Expect the engine to work to get the heavy sedan in motion, especially in environments with lots of lights and stop signs. The six-speed automatic transmission, while smooth, lacks the fuel-saving ratios found in modern 8- or 10-speed units. The upside is a proven powertrain with excellent reliability, a characteristic valued by Lexus buyers. Consider these numbers reasonable for what this car offers: secure all-weather performance and a dose of sporting character.

Annual fuel cost

The EPA estimates that the 2018 Lexus IS 300 AWD will cost $2,650 per year in fuel. That figure is based on driving 15,000 miles annually, using a combination of city and highway driving, and assumes national average fuel prices. Keep in mind that fuel prices fluctuate, and your individual driving habits will significantly impact your actual fuel costs. Aggressive acceleration and frequent short trips will push that number higher, while consistent highway cruising at moderate speeds has the potential to lower it.

Real-world expectations

While the EPA provides a standardized benchmark, real-world fuel economy often varies. Many owners find that they average around 20-24 MPG in mixed driving conditions. Factors like tire pressure, vehicle maintenance, and even the type of fuel used can all influence fuel efficiency. The IS 300’s V6 is designed to run without problems on regular 87 octane fuel. Premium fuel is not required, so sticking with regular unleaded can save you money at the pump. For those interested in seeing IS MPG across all years, there is plenty more data available.

How it compares

The 2018 Lexus IS 300 AWD competes in a crowded segment of luxury sport sedans. The BMW 330i xDrive, for instance, with its 2.0-liter turbocharged engine, achieves a combined EPA rating of 27 MPG. The Audi A4 quattro offers a similar combined rating of 27 MPG from its 2.0-liter turbo. The Infiniti Q50 AWD, equipped with its 3.0-liter twin-turbo V6, manages about 22 MPG combined. The Acura TLX SH-AWD with the V6 engine lands around 24 MPG combined. The IS 300 AWD buyer is likely aware of these differences and is willing to accept the fuel economy penalty for the Lexus’ overall package. For some, the Lexus’ reputation for reliability and smooth naturally aspirated power delivery outweighs the appeal of a more fuel-efficient, turbocharged competitor. You can find all Lexus fuel economy data on our site.

Tips to maximize efficiency

Gentle acceleration can make a noticeable difference. Avoid stomping on the gas pedal from a standstill. The 3.5L V6 delivers ample power, but using it carefully in city driving has a pronounced effect on MPG. Imagine that you have an open cup of coffee on the dash and you don’t want to spill it, accelerating smoothly and deliberately.

Maintain proper tire inflation, because underinflated tires create more rolling resistance, which decreases fuel economy. Check your tire pressure regularly and inflate them to the manufacturer’s recommended specifications, which can be found on the sticker inside the driver’s side door jamb.

Reduce unnecessary weight. Carrying extra cargo in the trunk or backseat adds weight to the vehicle, forcing the engine to work harder and consuming more fuel. Remove any items you don’t need to improve your gas mileage.

The IS 300’s all-wheel-drive system is designed for enhanced traction in slippery conditions, but it also adds weight and complexity that can slightly reduce fuel economy. In dry conditions, try to anticipate traffic flow to minimize braking and regain your speed smoothly in a forward momentum that isn’t hampered by excessive resistance between the tires and the road.