28 MPG combined is a modest figure for the 2016 Mercedes-Benz C300, especially considering its 2.0L turbocharged four-cylinder engine. While no one expects Prius-level efficiency from a C300, this number places it in the middle of the luxury sedan segment, meaning operating costs are worth considering for even badge-conscious buyers.

City and highway performance

The EPA estimates 25 MPG in the city and 33 MPG on the highway for the 2016 C300. The highway number is respectable because the engine cruises comfortably at higher speeds without significant fuel consumption. The city MPG suffers from stop-and-go traffic and the inherent inefficiencies of a conventional automatic transmission in urban settings. While the seven-speed automatic is generally smooth and responsive, it prioritizes a more engaging driving experience over maximizing fuel economy in heavy traffic.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2016 Mercedes-Benz C300 at $2,050. This is based on driving 15,000 miles per year and assumes national average fuel prices. It’s a standardized metric designed to let consumers directly compare the fuel expenses of different vehicles. Your actual fuel costs may vary depending on your driving habits, local fuel prices, and the gasoline grade you use. This is simply a benchmark, but a useful one when budgeting for the ownership of a C300. You can see C300 MPG across all years on our site.

Real-world expectations

While the EPA estimates provide a baseline, it’s important to understand what owners actually experience. Owners report that achieving the EPA’s 33 MPG highway rating is plausible on longer trips, especially when using cruise control and maintaining a steady speed. However, the 25 MPG city figure can be more challenging to replicate in congested urban areas. If your commute involves frequent stops and starts, expect numbers closer to the low 20s.

Overall, a combined MPG in the mid-to-high 20s is a reasonable expectation for most drivers.

How it compares

The 2016 C300’s fuel economy lags some of its competitors. For example, the contemporary BMW 328i (also a 2.0L turbo-4) often achieved slightly better real-world MPG. The Lexus IS 200t, with its similar engine displacement and driving dynamics, frequently saw a mile or two more per gallon on average. The Audi A4 Quattro, despite its all-wheel-drive system, manages comparable or even slightly improved fuel efficiency because of its refined engine and transmission. These fractional differences might seem insignificant individually, but can add up over the course of ownership. But those other brands may not offer what the Mercedes-Benz name does.

Review all Mercedes Benz fuel economy data to see how the brand performs.

Tips to maximize efficiency

The C300’s driving mode selector lets you choose between Comfort, Sport, Sport+, and Eco modes. Selecting Eco mode will remap the throttle response and shift points to prioritize fuel efficiency. While it might dampen the car’s sporty character, it can noticeably improve MPG, especially in city driving. Use it, even just for commuting.

Ensure your tires are properly inflated to the recommended pressure, which is usually found on a sticker inside the driver’s side doorjamb. Underinflated tires increase rolling resistance, which forces the engine to work harder and reduces fuel economy. A simple tire pressure check can pay dividends.

Avoid unnecessary acceleration and braking. Smooth, gradual driving enhances passenger comfort and improves fuel efficiency. Anticipate traffic conditions and maintain a steady pace whenever possible. This driving style uses the C300’s engine torque without demanding excessive fuel consumption.

Reduce the weight you carry in the vehicle. Extra cargo adds strain on the engine, affecting MPG. Remove any unnecessary items from the trunk or backseat to minimize this effect. A lighter car is inherently more fuel-efficient, no matter the engine.