Mercedes-Benz · 2016
AMG S65 6.0L 12-cyl
✓ EPA Verified
Premium Gasoline
Large Cars
Rear-Wheel Drive
City
13
MPG
Combined
15
MPG
Highway
20
MPG
Annual Fuel Cost
$3,850
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$1,700
more per year
Class Comparison — Large Cars
Bottom 0%
Better than 0 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 15 MPG
This vehicle
15 MPG
Class average
33 MPG
Class lowest
14 MPG
EPA Energy & Environment Scores
2
Energy Score
Out of 10
2
GHG Score
Out of 10
578 lbs
Annual CO₂
g/mile tailpipe CO₂
Yes
Start-Stop
Auto stop-start
Vehicle Specifications
Engine6.0L 12-cyl
TransmissionAutomatic 7-spd
DriveRear-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassLarge Cars
Start-StopYes
EPA Vehicle ID36753

15 MPG combined. Let’s be honest: nobody dropping $230,000+ on a 2016 Mercedes-Benz AMG S65 is prioritizing fuel efficiency. This isn’t about saving the planet; it’s about experiencing effortless, unrelenting power wrapped in the ultimate expression of luxury. Fuel consumption is simply a tax you pay for entry into this rarified world.

City and highway performance

You’ll see 13 MPG in the city and 20 MPG on the highway, according to the EPA. The city figure reflects the S65’s considerable weight and the engine’s thirst for fuel when constantly accelerating from stoplights. Highway performance, while relatively better, is still hardly economical. Expect to stop frequently on long road trips, not because the car can handle it, but because its 21.1-gallon fuel tank will be empty sooner than you think. Even at highway speeds, a gentle prod of the accelerator unleashes a surge of acceleration that makes efficiency an afterthought.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2016 Mercedes-Benz AMG S65 at $3,850. This figure is based on driving 15,000 miles per year, with a mix of city and highway driving, and using national average fuel prices. Given the S65’s requirement for premium fuel, those costs can climb even further, especially if fuel prices spike or if you find yourself frequently indulging in the engine’s prodigious power.

Real-world expectations

Real-world MPG will likely hover around the EPA estimates, although aggressive driving will push it lower. Owners who spend more time in stop-and-go city traffic can realistically expect even worse mileage. Conversely, those who primarily cruise on the highway, especially at consistent speeds, might see slightly better returns, though exceeding 20 MPG will be a challenge. Ultimately, the S65’s fuel economy is heavily dependent on driving style and conditions.

How it compares

Compared to other ultra-luxury performance sedans, the AMG S65 is predictably thirsty. A BMW M760i xDrive with its 6.6-liter V12 achieves a combined 16 MPG. The Porsche Panamera Turbo S E-Hybrid, despite its hybrid powertrain, manages only 22 MPG combined, largely due to its weight and performance focus. Even the less powerful AMG S63 with its 5.5-liter V8 achieves slightly better mileage, rated at 18 MPG combined. To the buyer of an S65, these distinctions are often academic. They are buying the ultimate expression of Mercedes-Benz luxury and performance, and a few MPG difference isn’t a deciding factor. Compare all Mercedes Benz fuel economy data to understand the brand’s overall MPG performance.

Tips to maximize efficiency

Embrace smooth, consistent acceleration. The AMG S65’s immense power encourages spirited driving, but gentler starts and smoother transitions between speeds will significantly improve fuel economy. Avoid abrupt acceleration and hard braking, as these actions force the engine to work harder and consume more fuel.

Use cruise control on the highway. Maintaining a constant speed minimizes unnecessary fluctuations in engine RPM and fuel consumption. Engage cruise control whenever possible on long stretches of highway, optimizing efficiency without sacrificing comfort.

Keep your tires properly inflated. Underinflated tires increase rolling resistance, forcing the engine to work harder and reducing fuel efficiency. Regularly check and maintain the recommended tire pressure to ensure optimal performance and economy.

Minimize idling. Idling consumes fuel without covering any distance. If you anticipate a prolonged stop, turn off the engine to conserve fuel and reduce emissions. Modern restarts are quick and efficient, so there’s little downside to this simple practice. Explore AMG MPG across all years to see how models have evolved.