22 MPG combined is an acceptable figure for the 2016 Lexus RX 350 AWD. It isn’t stellar, or class-leading, or even particularly impressive; it simply is. For the target buyer of this mid-size luxury crossover, a suburbanite prioritizing reliability, comfort, and a hassle-free ownership experience, that number likely falls into the “good enough” category. They aren’t chasing maximum efficiency; they’re chasing predictable luxury, and the RX reliably delivers.

City and highway performance

The EPA estimates for the 2016 RX 350 AWD break down to 19 MPG in the city and 26 MPG on the highway. The lower city figure reflects the RX’s weight (around 4,400 pounds), the less efficient nature of stop-and-go driving, and the fact that the 3.5-liter V6 needs to work harder to get the vehicle moving from a standstill. The 26 MPG highway rating is more respectable, showing the engine’s ability to cruise efficiently at consistent speeds. Some drivers may even exceed this number on long road trips, especially if they use cruise control effectively and avoid aggressive acceleration. The eight-speed automatic transmission helps optimize fuel consumption across the speed range, ensuring the engine is always operating within its most efficient RPM band.

Annual fuel cost

According to the EPA, the estimated annual fuel cost for the 2016 Lexus RX 350 AWD is $2,000. This figure is calculated based on driving 15,000 miles per year, with a specific percentage split between city and highway driving, and using national average fuel prices at the time of calculation. Of course, your actual fuel costs may vary depending on your driving habits, the type of roads you frequent, and prevailing fuel prices in your area, as this is simply an estimate. However, $2,000 provides a useful benchmark for budgeting your annual vehicle expenses.

Real-world expectations

While the EPA estimates provide a standardized benchmark, real-world fuel economy often diverges slightly. RX 350 AWD owners report numbers that fluctuate, depending on driving style and conditions. Expect MPG to dip noticeably in heavy traffic or during periods of sustained aggressive driving. Conversely, mindful driving, smooth acceleration, and consistent highway speeds can help you achieve numbers closer to, or even slightly above, the EPA’s estimates. Owners who live in areas with significant elevation changes will likely see lower MPG figures than those in flatter regions.

How it compares

The 2016 RX 350 AWD is in a competitive segment. The Acura MDX, another popular choice known for reliability, achieves a slightly better 22 MPG combined in its AWD configuration, and can sometimes reach 27 MPG on the highway with careful driving. The BMW X5 xDrive35i, while offering a sportier driving experience, gets around 20 MPG combined. The Volvo XC60 T6 AWD, with its supercharged and turbocharged engine, also delivers around 22 MPG combined. The RX 350’s fuel economy isn’t a strong selling point against these competitors, but the RX’s reputation for strong reliability and exceptional resale value are often more important factors for its target demographic. Those truly prioritizing fuel savings might also consider the RX 450h hybrid model, which offers significantly improved MPG, as well as RX MPG across all years, revealing the model’s fuel economy history. You can also review all Lexus fuel economy data for a broader brand comparison.

Tips to maximize efficiency

Avoid aggressive acceleration to conserve fuel. The RX 350 AWD’s V6 engine offers ample power, but stomping on the gas pedal frequently burns unnecessary fuel. Accelerate smoothly and gradually to help keep the engine in its most efficient operating range.

Maintain your vehicle properly. Regular oil changes, tire pressure checks, and air filter replacements contribute to optimal engine performance and fuel efficiency. Follow the Lexus recommended maintenance schedule to keep your RX running smoothly.

Reduce unnecessary weight. Carrying excessive cargo adds extra strain on the engine, resulting in lower fuel economy. Remove any items you don’t need from the trunk and passenger area to lighten the load.

Use cruise control on the highway. Cruise control helps maintain a consistent speed, reducing fluctuations in fuel consumption. Using cruise control on long, flat stretches of highway can significantly improve fuel efficiency.

Consider tire selection at replacement time. Low rolling resistance tires can improve your RX 350’s fuel economy. While you don’t want to compromise grip and safety, research tire options that prioritize fuel efficiency.