The 2018 Lexus RX 350 AWD achieves 22 MPG combined. This figure might not lead the class in fuel efficiency, but it usually isn’t a problem for RX owners who often value comfort, reliability, and the Lexus brand.

City and highway performance

The EPA estimates the 22 MPG combined rating is achieved from 19 MPG in the city and 26 MPG on the highway. The RX 350’s 3.5L V6 engine is smooth and responsive, but not particularly fuel-efficient. The eight-speed automatic transmission shifts well. In stop-and-go city driving, the RX 350 consumes the most fuel, because of constant acceleration and deceleration. Highway driving is better, but the RX’s aerodynamics and all-wheel-drive system still impact gas mileage, even at a constant speed.

Annual fuel cost

The EPA estimates the 2018 Lexus RX 350 AWD’s annual fuel cost at $2,000. This is calculated assuming 15,000 miles driven per year, using national average fuel prices. Your actual fuel cost will depend on your driving, fuel type, and local gas prices. Driving fast, short trips, and using premium fuel will increase your annual fuel expenditure. This is a factor when assessing the RX’s ownership costs, but many buyers are willing to pay for the RX’s luxury and reliability.

Real-world expectations

EPA estimates are only a baseline. Drivers in congested cities probably won’t consistently achieve 19 MPG in the city. However, those who primarily drive on highways might exceed 26 MPG on the highway. Factors such as driving style, tire pressure, and weather can influence your MPG. Monitor your fuel economy through the car’s trip computer or a fuel tracking app to gauge your vehicle’s actual performance. See all Lexus fuel economy data in our manufacturer section.

How it compares

The RX 350’s fuel economy is average for its class. The Acura MDX SH-AWD, with a V6 and all-wheel drive, gets an EPA-estimated 19 MPG city and 27 MPG highway. The BMW X3 xDrive30i, with a turbocharged four-cylinder engine, gets slightly better numbers, at 22 MPG city and 29 MPG highway. The Lincoln Nautilus, another option, gets around 20 city and 25 highway with its optional 2.7L turbo V6 and AWD. These differences can add up and influence a buyer who is very focused on fuel economy. Review RX MPG across all years in our model section. For buyers most interested in less gas, the RX 450h hybrid offers superior MPG, though it costs more initially.

Tips to maximize efficiency

Gentle acceleration and predictable braking are key to maximizing fuel economy in the RX 350. Avoid sudden bursts of speed and anticipate traffic to minimize braking. These changes can improve fuel consumption, particularly in city driving.

Ensure your tires are properly inflated to the recommended pressure. Underinflated tires increase rolling resistance, forcing the engine to work harder and consume more fuel. Check your tire pressures regularly.

Minimize idling time. Idling consumes fuel without going anywhere, so avoid unnecessary idling. Modern engines warm up quickly while driving, eliminating the need to idle in most situations.

Consider using cruise control on long highway drives. Maintaining a consistent speed optimizes fuel efficiency by reducing speed changes. Be mindful of traffic though, and disengage cruise control to maintain safe following distances.

Keep up with scheduled maintenance. Regular oil changes, air filter replacements, and spark plug maintenance ensure the engine runs smoothly and efficiently. A well-maintained engine consumes less fuel and operates at its best.