Mercedes-Benz · 2017
E400 4matic (station wagon) 3.0L 6-cyl
✓ EPA Verified
Premium Gasoline
Midsize Station Wagons
4-Wheel Drive
City
19
MPG
Combined
21
MPG
Highway
25
MPG
Annual Fuel Cost
$2,750
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$600
more per year
Class Comparison — Midsize Station Wagons
Bottom 15%
Better than 15 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 21 MPG
This vehicle
21 MPG
Class average
27 MPG
Class lowest
13 MPG
EPA Energy & Environment Scores
4
Energy Score
Out of 10
4
GHG Score
Out of 10
417 lbs
Annual CO₂
g/mile tailpipe CO₂
Yes
Start-Stop
Auto stop-start
Vehicle Specifications
Engine3.0L 6-cyl
TransmissionAutomatic 9-spd
Drive4-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassMidsize Station Wagons
Engine DescSIDI
Start-StopYes
EPA Vehicle ID38588

The 2017 Mercedes-Benz E400 4matic wagon’s 21 MPG combined rating isn’t its biggest selling point. It’s clear: no one buys *this* car for its fuel efficiency. They buy it for its unique combination of prestige, versatility, and understated cool. This is the choice for those who value substance over flash, practical elegance over ostentation. The E400 wagon buyer needs cargo space but refuses to drive an SUV, they want performance but scoff at the idea of a dedicated sports car. Fuel economy is a consideration, of course, but a lower priority.

City and highway performance

The E400 4matic wagon’s EPA ratings break down to 19 MPG in the city and 25 MPG on the highway. The city figure reflects stop-and-go driving, where the car’s weight and the 3.0L turbocharged V6 engine’s demands matter. The highway number is more respectable and achievable on longer cruises, thanks to the smooth-shifting 9-speed automatic transmission that keeps the engine in its optimal range. The 4matic all-wheel-drive system adds to the weight and lowers MPG, but it provides enhanced traction and peace of mind in less-than-ideal weather, important for many E400 wagon owners.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2017 Mercedes-Benz E400 4matic wagon at $2,750. This is based on driving 15,000 miles per year and using the national average fuel price at the time of estimation. It is a benchmark for comparing the E400’s running costs to other vehicles, but individual expenses may vary. If your daily commute is longer than average, or if fuel prices in your area are higher than the national average, expect to spend more. Likewise, conservative drivers who take shorter trips can expect lower annual fuel expenditures.

Real-world expectations

While the EPA estimates provide a starting point, real-world fuel economy will fluctuate based on driving style, road conditions, and maintenance. The E400’s turbocharger encourages spirited driving, which hurts fuel consumption. Short trips with cold starts also reduce fuel economy. Consistent highway driving at moderate speeds can often exceed the EPA’s 25 MPG rating. Owners who prioritize fuel economy can improve the numbers by ensuring proper tire inflation and adhering to the recommended maintenance schedule. Reviewing E400 MPG across all years can also provide owner reported context about fuel use.

How it compares

Compared to other vehicles in its class, the E400 4matic wagon’s fuel economy is average. The Volvo V90 T6 AWD, another stylish and luxurious wagon, achieves a similar 22 MPG combined. The Audi A6 Allroad, a competitor, achieves 21 MPG combined in its current trim. The Mercedes-Benz stands apart due to its driving experience and the cachet of the brand. If fuel efficiency is your sole priority, a hybrid SUV like the Lexus RX 450h (31 MPG combined) would be a more sensible choice. However, that vehicle lacks the cargo carrying capability of a wagon, and the RX projects a different image. Reviewing all Mercedes Benz fuel economy data can reveal the brand’s philosophy on efficiency.

Tips to maximize efficiency

Take advantage of the E400’s driving modes. Selecting “Eco” mode will remap the throttle response and shift points to prioritize fuel efficiency over performance which can be beneficial in congested city environments.

Avoid aggressive acceleration and braking. Smooth driving inputs place less stress on the engine and transmission, reducing fuel consumption. Anticipate traffic and maintain a steady pace.

The E400 4matic is equipped with a climate control system. Use it carefully, as overuse of air conditioning can place a heavy load on the engine, especially at lower speeds.

Ensure your tires are properly inflated. Underinflated tires create more rolling resistance, negatively impacting fuel economy. Check your tire pressures regularly and inflate them to the levels on the driver’s side doorjamb.

Consider using premium fuel. Although the E400 wagon may run on regular unleaded fuel, higher octane gasoline can improve engine performance and potentially increase fuel efficiency. Consult your owner’s manual.