22 MPG combined won’t win any awards, especially in 2017, but the Lexus IS 350 isn’t about chasing hypermiling numbers. It’s about delivering a smooth, responsive driving experience wrapped in Lexus refinement. The IS 350 appeals to those who prioritize a well-engineered naturally aspirated V6 and rear-wheel-drive dynamics over squeezing every last mile from a gallon of premium fuel. Its buyers understand that performance comes at a price, and they are willing to pay it.

City and highway performance

The EPA estimates for the 2017 Lexus IS 350 with the 3.5L V6 are 19 MPG in the city and 28 MPG on the highway. That city figure reflects the realities of stop-and-go driving, highlighting where the IS 350’s older engine design lags behind newer, turbocharged rivals. The highway number, however, demonstrates that it can achieve reasonable efficiency during steady-state cruising, which is welcome news for road trips.

Annual fuel cost

The EPA estimates that the annual fuel cost for the 2017 Lexus IS 350 is $2,650. This figure is based on driving 15,000 miles per year and using the national average fuel price for premium gasoline, which is required for optimal performance in the IS 350’s high-compression V6. Keep in mind that your actual fuel costs are likely to vary based on your individual driving habits, local fuel prices, and the number of miles you drive each year.

Real-world expectations

While the EPA estimates provide a useful benchmark, real-world fuel economy often deviates. Aggressive acceleration, frequent short trips, and consistent use of Sport mode will undoubtedly drag down your MPG. However, conscientious drivers who use the IS 350’s Eco mode and prioritize smooth, predictable throttle inputs can often get closer to the EPA’s highway number, even during mixed driving. Checking the IS MPG across all years can reveal trends others have experienced.

Consider that cold weather driving can also impact gas mileage as the engine requires more time to warm up to optimal operating temperatures.

How it compares

Compared to its rivals, the IS 350’s fuel economy lands somewhere in the middle. The BMW 340i (rated at 22 MPG combined), with its turbocharged inline-six, offers similar performance with theoretically better fuel efficiency. However, real-world testing often shows the BMW’s fuel economy to be highly dependent on driving style, potentially closing the gap. The Audi S4, with its supercharged V6, comes rated at 24 MPG combined, showcasing a slight premium in efficiency.

The Mercedes-Benz C43 AMG, also with a turbocharged V6, offered similar fuel efficiency. However, each of these competitors brings a different driving experience. The IS 350’s naturally aspirated engine delivers a linear power delivery, which is often preferred by enthusiasts, making the fuel economy a secondary consideration.

Tips to maximize efficiency

The 2017 Lexus IS 350 benefits from smooth and steady acceleration. Avoid abrupt acceleration or hard braking to conserve fuel. Mastering the art of anticipating traffic flow and maintaining a consistent speed minimizes wasted energy, and it will help you align with the EPA’s combined MPG rating, or even surpass it.

Engage the “Eco” mode whenever possible, especially for daily commutes. This mode adjusts throttle response and climate control settings to prioritize fuel efficiency. While it reduces the car’s responsiveness, it can make a noticeable difference in fuel consumption, particularly during stop-and-go driving. Remember that Eco mode will not turn your IS 350 into a Prius, but steady use will add up over time.

Ensure that your tires are properly inflated to the recommended pressure. Underinflated tires increase rolling resistance, which lowers fuel economy. Check tire pressure at least once a month and adjust as needed, following the specifications listed on the driver’s side door jamb.

Keep up with scheduled maintenance, including regular oil changes and air filter replacements. A well-maintained engine runs more efficiently, so adhering to Lexus’s recommended maintenance schedule is critical. Dirty air filters restrict airflow, forcing the engine to work harder and consume more fuel, and older oil degrades and reduces lubrication, putting extra strain on internal engine parts.

Minimize unnecessary weight in the vehicle. Excess cargo can significantly impact fuel economy, particularly in urban environments. Remove any items you don’t need from the trunk and passenger area to reduce the load on the engine. Considering all Lexus fuel economy data, this tip is important for any owner.