22 MPG combined isn’t going to win any hypermiling competitions, but it’s what you can expect if you want the Lexus GS 350 AWD’s strong V6 power, all-weather confidence, and unflappable reliability. This isn’t a car chasing ultimate efficiency; it’s offering a smooth, refined driving experience with the added sure-footedness of all-wheel drive, appealing to buyers who value predictability and long-term ownership costs over saving gas.

City and highway performance

The EPA estimates for the 2017 Lexus GS 350 AWD are 19 MPG in the city and 26 MPG on the highway. The city figure reflects stop-and-go traffic where the 3.5L V6 has to work harder, and the all-wheel-drive system adds drag. The highway MPG showcases the engine’s efficiency at steady speeds, indicating that longer road trips will yield closer to the advertised figure. The six-speed automatic transmission is geared to provide a balance between responsiveness and fuel conservation on the open road, although newer eight- and ten-speed transmissions in competitors provide better MPG.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2017 Lexus GS 350 AWD at $2,650. This figure is based on driving 15,000 miles per year and using national average fuel prices. Remember that your actual fuel costs may vary depending on your driving habits, the type of gas you use, and local fuel prices. The AWD system constantly drains efficiency, so those who don’t need it and live in a mild climate can look at RWD versions for small savings.

Real-world expectations

While the EPA estimates provide a baseline, real-world fuel economy for the 2017 Lexus GS 350 AWD often varies. Drivers who spend most of their time in heavy city traffic are likely to see numbers closer to 19 MPG, or even slightly below. Those who primarily drive on the highway, especially at a consistent pace, may be able to achieve or slightly exceed the 26 MPG estimate. Aggressive driving and frequent use of the sport mode will also negatively impact fuel economy. Owner-reported data on sites like Fuelly tends to show an MPG range reflecting this typical variance.

How it compares

The GS 350 AWD’s fuel economy places it in the middle of its class. The BMW 540i xDrive, with its turbocharged six-cylinder, achieves a noticeably better 23 MPG combined. The Mercedes-Benz E400 4MATIC (discontinued after 2018 and replaced with the E450) offered comparable power but similar MPG figures. The Acura TLX SH-AWD, while not strictly in the same luxury class as the GS, provides AWD and similar power with improved fuel economy (24 MPG combined). These comparisons matter to the GS buyer because they illustrate the fuel cost premium for Lexus’s renowned reliability and a naturally aspirated V6 engine. Also, investigate GS MPG across all years to see how this model year stacks up over time. For a broader perspective, review all Lexus fuel economy data on Lexus’s full line-up.

Tips to maximize efficiency

Use the “Eco” drive mode in everyday driving. The GS 350 AWD’s Eco mode adjusts throttle response and transmission mapping to prioritize fuel efficiency over performance. While it might feel slightly less responsive, the fuel savings can be noticeable, especially during city driving. Don’t be afraid to use this mode even on the highway for gradual acceleration.

Ensure your tires are properly inflated. Correct tire pressure reduces rolling resistance, which directly translates to better fuel economy. Check your tire pressure regularly and inflate them to the recommended pressure listed on the driver’s side doorjamb. A few PSI can make a measurable difference.

Minimize idling time. Letting your car idle for extended periods wastes fuel. If you’re waiting for someone or stopped for more than a minute, turn off the engine. Modern cars are designed to restart easily, and restarting consumes less fuel than idling.

Avoid aggressive driving habits. Rapid acceleration, hard braking, and high speeds consume more fuel. Drive smoothly and maintain a consistent speed whenever possible. Anticipate traffic flow and avoid unnecessary braking. The Lexus’ six-speed auto is not afraid to downshift aggressively if you drive that way, and it’ll cost you at the pump.

Regular maintenance is key to optimal fuel efficiency. Ensure your engine is properly tuned, and all fluids are at the correct levels. A well-maintained engine runs more efficiently and will deliver better fuel economy. Don’t skip those scheduled dealer visits!