The 2016 Mercedes-Benz GLE350 4matic, with its 3.5L V6, gets 19 MPG combined. It’s a figure that won’t win any awards for being green, but it isn’t a deal-breaker for buyers who prioritize luxury, capability, and the Mercedes-Benz brand. This vehicle is built for comfort and presence, and fuel economy is a secondary consideration.

City and highway performance

The EPA estimates for the GLE350 4matic are 18 MPG in the city and 22 MPG on the highway. The city figure reflects the demands on the engine during stop-and-go driving. The 22 MPG highway rating is thanks to the seven-speed automatic transmission, which allows the engine to cruise at low RPMs at highway speeds. If you accelerate quickly or maintain speeds above 75 mph, expect the highway number to decrease.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2016 Mercedes-Benz GLE350 4matic at $3,050. This figure is based on driving 15,000 miles per year, with a mix of city and highway driving, using the national average fuel price at the time of calculation. Individual fuel costs will vary based on driving habits, local fuel prices, and fuel type, but this $3,050 figure is a reasonable estimate for the typical owner.

Real-world expectations

EPA estimates offer a standardized measure, but real-world MPG can vary. Drivers who accelerate hard or those who frequently use the GLE350’s power for towing or hauling cargo will likely see fuel economy closer to the city rating, or even lower. On the other hand, drivers who accelerate smoothly, anticipate traffic, and drive mostly on the highway might achieve slightly better than the EPA highway estimate. Owner forums and online fuel tracking resources can provide a broader view of real-world GLE350 MPG across all years.

How it compares

The GLE350’s fuel economy is similar to others in its class. A BMW X5 xDrive35i, with its turbocharged inline-six, achieves a similar 18 MPG city and 25 MPG highway. An Acura MDX SH-AWD, with its newer V6, gets slightly better fuel economy at 19 MPG city and 27 MPG highway, but lacks the luxury of the Mercedes. The Lexus RX 350 is known for its reliability and gets 20 MPG city and 27 MPG highway. These differences may seem minor, but they can add up to hundreds of dollars in fuel costs each year. For buyers considering these vehicles, fuel economy is one of many factors, including price, features, performance, and brand.

You’ll find all Mercedes Benz fuel economy data on our website.

Tips to Maximize Efficiency

Smooth, steady acceleration is key to good fuel economy in the GLE350. The 3.5L V6 provides plenty of torque, so you don’t need to press the gas pedal hard. Anticipate traffic and maintain a consistent speed to avoid unnecessary acceleration and braking.

Make sure your tires are inflated to the recommended pressure. Underinflated tires increase rolling resistance, which reduces fuel efficiency. Check your tire pressure regularly, especially when the temperature changes.

Reduce aerodynamic drag by avoiding roof racks or cargo carriers when you can. These accessories can increase wind resistance, especially at highway speeds, which lowers fuel economy. Remove them when you don’t need them.

Use cruise control on the highway to maintain a consistent speed and help to optimize fuel efficiency. While adaptive cruise control is useful, maintaining a steady speed yourself can be more efficient if you can anticipate traffic flow.

Regular maintenance is important for good fuel economy. Make sure your GLE350 has routine servicing, including oil changes, air filter replacements, and spark plug maintenance. A well-maintained engine runs more efficiently.