23 MPG combined isn’t going to win any fuel efficiency awards, but it’s adequate for the 2016 Mercedes-Benz E400 Coupe. This isn’t a vehicle purchased by penny-pinchers or hypermilers; it’s for those who value style, comfort, and a refined driving experience. Fuel economy is less important than the sensations delivered by that smooth, turbocharged 3.0L six-cylinder engine and the confident stance of a pillarless coupe. The E400 Coupe buyer accepts this fuel consumption as the price of ownership.

City and highway performance

The EPA estimates 20 MPG in city driving and 29 MPG on the highway. These figures reflect the E400’s character. In stop-and-go traffic, the turbocharged engine requires more fuel to overcome its weight and deliver the expected responsiveness. However, on the open road, the seven-speed automatic transmission allows the engine to cruise at lower RPMs, contributing to respectable highway fuel economy. Your individual results will vary depending on driving style and the nature of your commute.

Someone with a long, uninterrupted highway commute will likely see figures closer to, or even exceeding, the EPA’s 29 MPG estimate.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2016 Mercedes-Benz E400 Coupe at $2,500. This calculation is based on driving 15,000 miles per year using the EPA’s combined fuel economy rating and assuming national average fuel prices. It serves as a benchmark, but do not take this figure as gospel. Personal driving habits, local fuel prices, and even weather conditions will significantly impact your actual fuel expenses. Someone who drives mostly in the city, with a heavier foot, will inevitably spend more. You can dig deeper into E400 MPG across all years to see data from varied owner experiences.

Real-world expectations

Owners often report slightly lower than EPA estimates in combined driving scenarios. You can expect something in the area of 20-24 MPG in mixed driving, with the potential for slightly better results on long highway trips. Aggressive acceleration and frequent use of the sport modes will undoubtedly reduce fuel economy. Consistent, gentle driving habits are critical for achieving numbers closer to the EPA estimates.

The E400 is a heavy car packed with technology, and that all comes at a price. If you aren’t mindful, those numbers will plummet.

How it compares

Compared to its rivals, the 2016 E400 Coupe’s fuel economy is competitive but not class-leading. A 2016 BMW 435i Coupe, with its 3.0L turbocharged inline-six, achieves about 25 MPG combined, edging out the E400. The Audi A5 Coupe, with its smaller 2.0L turbocharged four-cylinder, can achieve up to 26 MPG combined, a benefit for buyers prioritizing less gas. Even the more powerful BMW 640i Coupe achieves a similar 24 MPG combined; horsepower isn’t always a fuel-economy disaster. These comparisons are helpful because while they aren’t primarily focused on fuel efficiency, they still want to know they are making a reasonable choice within their segment. It is worth checking all Mercedes Benz fuel economy data to see how the E400 stacks up against siblings as well, should you want to stay loyal to the brand.

Tips to maximize efficiency

Use the “ECO” driving mode whenever possible. This mode optimizes shift points and throttle response to prioritize fuel efficiency. While it may slightly reduce responsiveness, it can noticeably improve fuel economy in everyday driving.

Maintain proper tire inflation. Underinflated tires increase rolling resistance, forcing the engine to work harder and consume more fuel. Check your tires regularly and ensure they are inflated to the recommended pressure, usually found on a sticker inside the driver’s side doorjamb. Every bit helps considering how complex and weighty vehicles have become.

Avoid aggressive acceleration and braking. Smooth, gradual changes in speed are far more fuel-efficient than sudden bursts of power. Anticipate traffic flow and maintain a consistent speed whenever possible. The E400’s turbo engine responds readily but requires a careful right foot to achieve optimal mileage.

Reduce unnecessary weight. Carrying excess cargo in the trunk adds to the vehicle’s overall weight, reducing fuel economy. Remove any items you don’t need to conserve energy. Even a few small items can add up.

Consider the grade of gasoline you’re using. While the E400 doesn’t strictly require premium fuel (check your owner’s manual), some drivers report improved performance and fuel economy when using higher-octane gasoline. The increased cost of premium may offset any gains in efficiency, so experiment to see what works best for your driving style and conditions.