22 MPG combined won’t top any fuel economy charts, but for the 2016 Mercedes-Benz CLS400 4matic, it’s an acceptable trade-off for the sleek styling and confident performance. CLS400 buyers aren’t prioritizing ultimate fuel efficiency; they want a statement of taste and understated power, and are willing to pay more at the pump.

City and highway performance

The EPA estimates 19 MPG in the city and 26 MPG on the highway for the 2016 CLS400 4matic. This difference reflects the car’s performance. In urban environments, the 3.0L turbocharged V6 works harder in stop-and-go traffic, resulting in lower fuel economy.

On the open road, the smooth-shifting 7-speed automatic transmission and the engine’s efficiency at cruising speeds allow it to travel further on a gallon. These figures are achievable with a measured driving style, but exploiting the engine’s responsive power delivery can diminish them.

Annual fuel cost

The EPA estimates you’ll spend about $2,650 per year fueling the 2016 Mercedes-Benz CLS400 4matic. This is based on driving 15,000 miles annually, using the national average fuel price at the time of calculation. Fluctuating gas prices and individual driving habits will impact this number.

A lead-footed driver in a city with high fuel costs could exceed this estimate, while a careful driver who primarily uses it for highway cruising might spend less. This estimate provides a benchmark for the overall ownership cost, and you can review all Mercedes Benz fuel economy data to find one that better fits your budget.

Real-world expectations

While the EPA estimates provide a comparison, real-world MPG varies. The CLS400’s turbocharger encourages spirited driving, which can affect fuel consumption. Short trips where the engine doesn’t reach optimal operating temperature also decrease fuel economy.

Long highway journeys, especially with cruise control engaged, can meet or slightly exceed the EPA’s 26 MPG highway estimate. Owners who prioritize fuel saving may approach the higher end of the scale. Those who plan to see how high it gets should also check out CLS400 MPG across all years for comparison.

How it compares

In the luxury four-door coupe segment, the CLS400’s fuel economy is typical. For example, the 2016 BMW 640i Gran Coupe with xDrive, using a 3.0L turbocharged inline-six, offers a comparable 22 MPG combined, with 20 MPG city and 29 MPG highway. The Audi A7 3.0T, another competitor, delivers around 24 MPG combined.

The CLS400 isn’t the most fuel-efficient option, but it isn’t significantly worse than its rivals. A buyer considering the CLS400 is cross-shopping these other models and understands that fuel economy is not the primary differentiator. They are more interested in styling, performance, and brand cachet, and are willing to accept slightly below-average MPG.

Tips to maximize efficiency

Avoid constantly using the engine’s turbocharger. Gentle acceleration and anticipating traffic flow will minimize fuel consumption. The CLS400’s engine delivers ample torque at low RPMs, so there’s no need to constantly rev the engine to achieve adequate performance.

Use the car’s driving mode selector. “Eco” mode optimizes vehicle settings to promote fuel efficiency, including throttle response and transmission shift points. It may slightly compromise performance, but it can noticeably improve MPG, especially in city driving.

Ensure your tires are properly inflated and your car is well-maintained. Low tire pressure increases rolling resistance and reduces fuel economy. Regular maintenance, including oil changes and air filter replacements, keeps the engine running efficiently.

Minimize unnecessary weight and drag. Remove any items from the trunk you don’t need and avoid using roof racks or cargo carriers when they’re not required. The cleaner the car cuts through the air, the less fuel it consumes.

Plan your routes to avoid stop-and-go traffic and congested areas, if possible. Maintaining a steady speed on the highway is far more fuel-efficient than repeatedly accelerating and braking in heavy traffic.