Lexus · 2016
IS 350 AWD 3.5L 6-cyl
✓ EPA Verified
Premium Gasoline
Compact Cars
All-Wheel Drive
City
19
MPG
Combined
21
MPG
Highway
26
MPG
Annual Fuel Cost
$2,750
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$600
more per year
Class Comparison — Compact Cars
Bottom 13%
Better than 13 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 21 MPG
This vehicle
21 MPG
Class average
33 MPG
Class lowest
12 MPG
EPA Energy & Environment Scores
5
Energy Score
Out of 10
5
GHG Score
Out of 10
415 lbs
Annual CO₂
g/mile tailpipe CO₂
No
Start-Stop
Not equipped
Vehicle Specifications
Engine3.5L 6-cyl
TransmissionAutomatic (S6)
DriveAll-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassCompact Cars
Engine DescSIDI & PFI
Start-StopNo
EPA Vehicle ID36894

The 2016 Lexus IS 350 AWD, with its 3.5L V6, achieves an EPA-estimated 21 MPG combined. This isn’t a fuel-sipper, but it’s also not the main concern for buyers drawn to this Lexus. They prioritize athletic driving dynamics, stylish looks, and the confidence of all-wheel drive, accepting the trade-off at the pump for a car that delivers on those aspects.

City and highway performance

The EPA estimates show distinct performance in different driving scenarios. The IS 350 AWD gets around 19 MPG in the city. This number reflects urban driving’s stop-and-go nature and the engine’s need to work harder from a standstill. On the open highway, the number climbs to 26 MPG, showcasing the engine’s efficiency when cruising at a consistent speed. This difference reveals that careful driving habits, particularly on longer trips, can noticeably influence overall fuel consumption. These numbers aren’t class-leading, but they represent a powerful V6 engine paired with a six-speed automatic transmission delivering engaging performance.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2016 Lexus IS 350 AWD at $2,750. This figure is based on driving 15,000 miles per year and using national average fuel prices. This is an estimate, and your actual fuel costs can vary significantly depending on your driving habits, the type of fuel you use, and local fuel prices. $2,750 gives potential buyers a concrete number to consider when factoring in the overall cost of ownership.

Real-world expectations

The IS 350 AWD offers a sport mode for enhanced throttle response and more aggressive shift points. Consistent use of this mode will negatively impact fuel economy. Drivers who appreciate the car’s performance capabilities will likely experience real-world MPG that aligns closely with the EPA estimates, perhaps even slightly lower if the car is primarily driven in city environments or with aggressive driving. However, drivers prioritizing fuel efficiency and adopting smoother driving habits can potentially see numbers closer to, or even slightly above, the EPA’s highway estimate on longer journeys.

How it compares

Compared to its rivals, the 2016 Lexus IS 350 AWD’s fuel economy lands in a specific segment of the market. For example, a BMW 340i xDrive from the same year often boasts a slightly better combined MPG, nearing 25 MPG, thanks to its turbocharged inline-six engine. The Audi S4, another popular contender, achieves a similar combined figure, often around 24 MPG. These advantages in fuel efficiency are meaningful, but they don’t determine the entire buying decision. The decision to purchase the IS 350 AWD instead of the BMW or Audi depends on factors like Lexus’ proven reliability record, the IS’ distinctive styling, and driving feel, which can make the fuel economy difference a secondary concern. Buyers who want to compare all Lexus fuel economy data can do so easily. You can also research IS MPG across all years to compare fuel economy across the IS model line.

Tips to maximize efficiency

The IS 350 AWD uses a naturally aspirated V6, so avoid aggressive acceleration if possible. Gradual acceleration allows the engine to operate more efficiently, reducing fuel consumption without sacrificing too much performance in everyday driving. Quick bursts of speed, while enjoyable, will decrease your MPG.

Ensure that your tires are properly inflated. Underinflated tires increase rolling resistance, forcing the engine to work harder and consume more fuel. Regularly check your tire pressure and maintain it at the recommended level, which is typically found on a sticker inside the driver’s side door jamb.

Reduce unnecessary weight in the vehicle. Carrying excessive cargo adds to the overall weight of the car, impacting fuel economy. Remove any items you don’t need, especially heavier objects, to improve efficiency.

Plan your routes strategically to avoid stop-and-go traffic. Idling consumes fuel without covering any distance. Optimize your driving routes to minimize time spent in congested areas and maximize the time spent cruising at consistent speeds.

Consider using the car’s Eco mode, if equipped. Eco mode typically adjusts throttle response and shift points to prioritize fuel efficiency, potentially reducing acceleration and performance slightly but improving fuel economy. The IS 350’s sport mode is fun, but best saved for spirited driving.