The 2015 Mercedes-Benz ML350 4matic 3.5L 6-cyl gets 19 MPG combined, a figure that most buyers of this mid-size luxury SUV find acceptable. The ML350 delivers a comfortable, capable, and prestigious vehicle with all-weather capability thanks to its 4matic all-wheel drive system. The ML350 4matic prioritizes a smooth, composed driving experience and a level of refinement that appeals to established professionals or families who value luxury and safety above saving money on fuel. For them, 19 MPG is a reasonable price to pay.

City and highway performance

The EPA estimates for the 2015 ML350 4matic are 18 MPG in the city and 22 MPG on the highway. The city figure reflects stop-and-go traffic, where the ML350’s weight and engine inefficiencies are apparent. The highway number is better. The 7-speed automatic transmission keeps the engine in its most efficient range at cruising speeds. Long, straight stretches of highway driving will yield the best numbers, while frequent acceleration for passing will drop the MPG closer to the combined rating.

Annual fuel cost

According to the EPA, the annual fuel cost for the 2015 Mercedes-Benz ML350 4matic is exactly $3,050. This is based on driving 15,000 miles per year and using national average fuel prices at the time of testing. Individual driving habits and local fuel costs can significantly influence the real-world cost. A driver in congested city conditions with a heavy foot will spend more than $3,050 per year on fuel. However, a driver who focuses on maximizing fuel efficiency and drives primarily on highways might spend less. For more information, see all Mercedes Benz fuel economy data.

Real-world expectations

The EPA estimates provide a baseline, but real-world fuel economy can vary. The ML350’s 3.5L V6 is a smooth and responsive engine, but it’s easy to use its power, especially when merging onto highways or overtaking other vehicles. Driving style also plays a role. Aggressive acceleration and hard braking will dramatically reduce fuel economy.

Terrain matters too. Hilly or mountainous areas will generally result in lower MPG figures than flat roadways. These SUVs are often used to haul cargo or passengers; added weight can significantly hurt fuel efficiency.

How it compares

The 2015 Mercedes-Benz ML350 4matic isn’t a leader in its class regarding fuel economy, but it also isn’t the worst. A 2015 BMW X5 xDrive35i, a direct competitor, posts a similar 19 MPG combined, but delivers a slightly better 18 city / 25 highway, potentially offering better efficiency on long trips. A 2015 Acura MDX SH-AWD, known for its blend of practicality and efficiency, achieves 21 MPG combined (18 city / 27 highway), making it a more economical alternative. The Lexus RX 350, another popular choice, boasts 22 MPG combined.

While the ML350’s 19 MPG might seem underwhelming compared to these, buyers often prioritize the Mercedes-Benz brand, the ML350’s comfort, and its strong resale value, making fuel economy less important. If you’re considering other options, check out the ML350 MPG across all years.

Tips to maximize efficiency

Maintain proper tire inflation. Under-inflated tires increase rolling resistance and negatively impact fuel economy. Check your tire pressure regularly and inflate them to the manufacturer’s recommended specifications, which can be found on a sticker inside the driver’s side doorjamb.

Avoid aggressive driving habits. Rapid acceleration and hard braking consume more fuel. Practice a smooth acceleration, anticipate traffic conditions to minimize unnecessary braking, and drive like you have a cup of coffee on the dash.

Reduce unnecessary weight. Carrying heavy cargo or equipment in your ML350 puts extra strain on the engine. Remove unnecessary items to improve fuel efficiency. The less weight you haul, the better gas mileage you can expect.

Use cruise control on the highway. Maintaining a consistent speed on long drives can significantly improve fuel economy. Cruise control helps to avoid speed fluctuations and keeps the engine operating at its most efficient level. With the ML350’s comfortable seats, this habit is easy to maintain.

Keep up with routine maintenance. Regular oil changes, air filter replacements, and tune-ups ensure that your engine runs well. A well-maintained engine is a more fuel-efficient engine.