Mercedes-Benz · 2015
E400 4matic (station wagon) 3.0L 6-cyl
✓ EPA Verified
Premium Gasoline
Midsize Station Wagons
4-Wheel Drive
City
19
MPG
Combined
22
MPG
Highway
26
MPG
Annual Fuel Cost
$2,650
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$500
more per year
Class Comparison — Midsize Station Wagons
Bottom 20%
Better than 20 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 22 MPG
This vehicle
22 MPG
Class average
27 MPG
Class lowest
13 MPG
EPA Energy & Environment Scores
5
Energy Score
Out of 10
5
GHG Score
Out of 10
410 lbs
Annual CO₂
g/mile tailpipe CO₂
Yes
Start-Stop
Auto stop-start
Vehicle Specifications
Engine3.0L 6-cyl
TransmissionAutomatic 7-spd
Drive4-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassMidsize Station Wagons
Engine DescSIDI
Start-StopYes
EPA Vehicle ID35877

22 MPG combined isn’t going to win any fuel efficiency awards, but for the 2015 Mercedes-Benz E400 4matic wagon, driven by its target demographic, it’s an acceptable compromise. This isn’t a car bought by penny-pinchers seeking ultimate efficiency; it’s for buyers who prioritize a unique blend of luxury, utility, performance, and all-weather capability. These buyers understand the realities of driving a relatively heavy, turbocharged, all-wheel-drive wagon.

City and highway performance

The EPA estimates 19 MPG in the city and 26 MPG on the highway for the E400 4matic wagon. The city figure reflects urban driving, where the engine spends more time idling and accelerating. The highway figure is more optimistic, assuming consistent speeds and less demand on the engine. However, the reality for many E400 wagon owners involves a mix of both, with suburban commutes involving congested parkways, family road trips loaded with gear, and weekend adventures that might include rougher terrain. In those conditions, expect numbers closer to the combined EPA estimate. Its 7-speed automatic transmission helps optimize fuel economy at highway speeds, but the 3.0L turbocharged V6 needs fuel to deliver its power.

Annual fuel cost

The EPA estimates an annual fuel cost of $2,650 for the 2015 Mercedes-Benz E400 4matic wagon. This figure is based on driving 15,000 miles per year and using national average fuel prices at the time of the calculation. Prices at the pump always fluctuate, but this provides a benchmark for prospective buyers within the car’s life-cycle. It’s a useful point of comparison against other vehicles considered by those browsing all Mercedes Benz fuel economy data.

Real-world expectations

While the EPA estimates provide a baseline, real-world fuel economy can vary significantly depending on driving habits, traffic conditions, and even your region’s topography. Aggressive acceleration, frequent hard braking, and extended idling will all negatively impact fuel economy. Properly inflated tires, regular maintenance, and avoiding excessive cargo weight can help optimize efficiency. Keep in mind that winter blends of gasoline often result in slightly lower fuel economy, especially in colder climates.

How it compares

Compared to other vehicles in its class, the 2015 E400 4matic wagon’s fuel economy is right in line. For example, the BMW 535i xDrive wagon, a key competitor, achieves similar MPG figures. The Audi A6 allroad, another popular choice for those seeking a luxurious wagon with all-wheel drive, also resides within a similar fuel economy bracket. Even newer, more technologically advanced wagons like the Volvo V90 Cross Country aren’t significantly more efficient, highlighting the inherent trade-offs between performance, luxury, and less gas consumption in this segment. For more information, visit the E400 MPG across all years.

Tips to maximize efficiency

The E400’s turbocharged engine responds well to smooth acceleration. Avoid aggressive bursts of speed and try to maintain a steady throttle position as much as possible. Anticipate traffic flow and coast when appropriate to minimize the need for hard braking.

Regularly check your tire pressure and keep them inflated to the recommended levels. Underinflated tires increase rolling resistance, which reduces fuel economy. And remove any unnecessary cargo from the vehicle. Extra weight puts additional strain on the engine, leading to higher fuel consumption.

The 7-speed automatic transmission is designed for efficiency. Use “Comfort” mode for daily driving, as it prioritizes fuel economy, but the “Sport” mode can be fun on occasion, it will noticeably impact your MPG. Highway driving with cruise control engaged will provide improved mileage as well.

Consider using a fuel additive designed to clean fuel injectors. Clean injectors ensure proper fuel atomization, which optimizes combustion and improves fuel economy. However, make sure the additive is compatible with the E400’s engine.