22 MPG combined isn’t going to win any awards, but it’s a perfectly reasonable figure for the 2015 Mercedes-Benz E350 Coupe, a vehicle primarily concerned with style, comfort, and a certain effortless cool. This isn’t about hypermiling; it’s about arriving looking like you didn’t have to try too hard. The E350 Coupe buyer appreciates performance but prioritizes a smooth, refined experience over outright efficiency. They’re willing to trade a few MPGs for the silky-smooth power delivery of that 3.5L V6.

City and highway performance

The EPA estimates highlight the E350 Coupe’s balanced performance. The 19 MPG city rating reflects the fuel demands of stop-and-go traffic, where the engine works harder and the aerodynamic shape contributes less. Conversely, the 28 MPG highway figure shows the benefits of the 7-speed automatic transmission and the V6’s ability to cruise efficiently at higher speeds. This spread suggests the E350 Coupe is best suited for drivers who split their time between city commutes and longer highway journeys, a pattern common among those who seek the Coupe’s blend of everyday usability and weekend escape capability. Those exclusively in the city might find the MPG less palatable, while those consistently on the highway will fare somewhat better.

Annual fuel cost

The EPA estimates an annual fuel cost of $2,650 for the 2015 Mercedes-Benz E350 Coupe. This figure is based on driving 15,000 miles per year, using a blend of city and highway driving, and assumes national average fuel prices. Remember that your actual fuel costs will vary depending on your driving habits, fuel prices in your area, and how often you drive, but $2,650 provides a good benchmark for what to expect.

Real-world expectations

While the EPA provides a standardized test, real-world MPG often differs. Aggressive driving, frequent short trips, and neglecting maintenance can all negatively impact fuel economy. Conversely, consistently smooth acceleration, anticipating traffic flow, and ensuring proper tire inflation can help you approach, or even slightly exceed, the EPA estimates. The E350 Coupe, with its emphasis on a relaxed driving experience, tends to reward a gentler touch. Owners who embrace a more leisurely driving style and maintain the car diligently are more likely to see figures closer to the EPA’s 22 MPG combined.

How it compares

Compared to rivals, the 2015 E350 Coupe’s fuel economy is within the expected range for its segment. The BMW 435i Coupe, for example, achieves around 25 MPG combined with its turbocharged inline-6. Meanwhile, the Audi A5 Coupe, equipped with its 2.0-liter turbocharged four-cylinder, offers approximately 26 MPG combined. The Cadillac ATS Coupe manages about 22 MPG combined with its standard 2.0T engine. While the German competitors offer slightly better fuel economy they may lack the classic, refined aesthetic that attracts buyers to all Mercedes Benz fuel economy data. This comparison matters because it illustrates the compromises inherent in choosing a luxury coupe. Buyers must weigh performance, style, and fuel efficiency to determine the best fit for their needs. Those seeking maximum MPG might lean towards the Audi or BMW, while those prioritizing a larger engine and a smoother ride may find the E350 Coupe’s trade-off acceptable. Comparing E350 MPG across all years can also help inform the decision.

Tips to maximize efficiency

One key to improving fuel economy in the E350 Coupe is smooth acceleration. The 3.5L V6 offers ample power, so there’s no need to aggressively stomp on the accelerator. Gentle, progressive acceleration allows the engine to operate more efficiently and minimizes fuel consumption, aligning perfectly with the car’s relaxed, luxurious character.

Regular maintenance, especially tire inflation, is critical. Underinflated tires create more rolling resistance, forcing the engine to work harder and reducing fuel economy. Check and adjust your tire pressure regularly to the recommended level, typically found on a sticker inside the driver’s side door or in the owner’s manual. This simple step can noticeably improve your MPG without sacrificing ride quality.

Use cruise control on long highway stretches. Maintaining a consistent speed not only reduces driver fatigue but also minimizes unnecessary acceleration and deceleration, leading to more consistent and efficient fuel consumption. The E350 Coupe’s cruise control system is designed for comfortable, long-distance driving, making it an excellent tool for maximizing highway MPG.

Minimize idling time. Letting the engine idle for extended periods wastes fuel and contributes to emissions. If you anticipate stopping for more than a minute or two, it’s generally more fuel-efficient to turn off the engine and restart it when you’re ready to go. This is especially true in urban environments where idling can be a frequent occurrence.