19 MPG combined. That number isn’t going to win any awards, but the Cadillac CT4-V with its 3.6L V6 isn’t about winning efficiency trophies. It’s about delivering a specific driving experience ,a balance of accessible performance and daily usability that appeals to a certain type of buyer. This is someone who appreciates the responsiveness of a naturally aspirated engine, the immediacy of its power delivery, and the engaging sound it produces, even if it means sacrificing a few MPGs. They know what they’re getting into, and they’re generally okay with the tradeoff.

City and highway performance

The EPA estimates the CT4-V at 16 MPG in the city and 24 MPG on the highway. The city figure reflects stop-and-go traffic, where the V6 works harder to move the sedan. The 10-speed automatic transmission does its best to keep the engine in its optimal range, but frequent acceleration and braking affect mileage. On the open road, the CT4-V does better. At cruising speeds, the engine settles, and the transmission selects higher gears, improving efficiency. The urge to accelerate and experience that V6 surge can erase any gains. This car encourages spirited driving, and resisting temptation is key to achieving anything close to the EPA’s highway estimate.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2025 Cadillac CT4-V with the 3.6L V6 is about $3,050. This is based on driving 15,000 miles per year, with 45% of those miles in the city and 55% on the highway. It also assumes the vehicle is fueled using the national average fuel price when calculated. These numbers are estimates. Your actual fuel costs will vary depending on your driving habits, the roads you drive on, and local fuel prices. But $3,050 is a good benchmark when budgeting for the cost of ownership.

Real-world expectations

EPA estimates provide a comparison point, but real-world fuel economy can differ. CT4-V drivers who spend most of their time in urban areas are likely to see figures closer to the 16 MPG city rating, or even slightly below. Drivers who frequently take long highway trips, maintaining consistent speeds, may be able to match or exceed the 24 MPG highway number. Expect an average of 17-21 MPG in mixed driving conditions, depending on how aggressively you drive. Someone who regularly uses the car’s performance will see lower numbers. Someone who tries hypermiling can likely do better, but this is not really the car for that.

How it compares

The CT4-V’s fuel economy places it in a specific spot relative to its competitors. The BMW M340i with its inline-six turbo offers an improvement, achieving 26 MPG combined. The Audi S4 with its turbocharged V6 generally manages slightly better numbers, around 24 MPG combined. The Lexus IS350, with its naturally aspirated V6, often delivers slightly better mileage in real-world driving. None of those cars duplicate the character and feel of the CT4-V’s engine. This makes the difference to the buyer. They are selecting for the driving experience, not purely for maximizing fuel efficiency. For more, examine all Cadillac fuel economy data and more details such as CT4 MPG across all years.

Tips to maximize efficiency

The CT4-V isn’t designed for maximum fuel efficiency, but you can improve its mileage. Avoid hard acceleration and maintain a steady speed on the highway. Anticipate traffic flow and avoid unnecessary braking, which wastes energy. Use cruise control on the highway to maintain a consistent speed and minimize throttle inputs.

Make sure your tires are properly inflated. Underinflated tires increase rolling resistance, which reduces fuel economy. Check your tire pressure regularly and inflate them to the recommended pressure listed on the sticker inside your driver’s side door. Even a small difference in tire pressure can impact fuel consumption.

Minimize idling. Idling wastes fuel and contributes to emissions. If you’re going to be stopped for more than a minute or two, turn off the engine. Modern cars restart quickly and efficiently, so there’s no need to let the engine sit running unnecessarily.

Keep your car well-maintained. Regular maintenance, such as oil changes and air filter replacements, can help improve fuel economy. A clean air filter allows the engine to breathe more easily, which improves combustion efficiency. Following the manufacturer’s recommended maintenance schedule helps performance and fuel efficiency.

Consider your driving mode. The CT4-V offers various driving modes, including a more fuel-efficient setting. This mode may slightly dampen throttle response and steering feel, but it can help reduce fuel consumption in everyday driving when maximum performance isn’t required.