22 MPG combined. That’s the EPA’s sticker number for the 2024 Lexus IS 350 AWD with its naturally aspirated 3.5L V6. It’s a figure that won’t have EV evangelists rushing to showrooms, nor will it deter the buyer who appreciates the IS 350’s dynamic handling, unmistakable styling, and Lexus’s hallmark reliability. This isn’t a car purchased for ultimate efficiency; it’s a statement. A statement that says “I value driving pleasure and distinctive design over squeezing every last mile from each gallon.” It’s a deliberate trade-off, and one that the typical IS 350 buyer makes with open eyes and a clear understanding of priorities.

City and highway performance

The EPA estimates the IS 350 AWD achieves 19 MPG in city driving and 26 MPG on the highway. The city figure reflects the realities of stop-and-go traffic, where the V6 engine spends more time at low speeds or idling, impacting fuel consumption. The highway number is more respectable, aided by the six-speed automatic transmission and the engine’s ability to cruise efficiently at higher speeds. However, aggressive driving, even on the highway, will quickly diminish those gains. Understanding this spread, and knowing your typical driving environment, is crucial to managing expectations with the IS 350.

Annual fuel cost

According to the EPA, the annual fuel cost for the 2024 Lexus IS 350 AWD is estimated at $2,650. This calculation is based on driving 15,000 miles per year and using national average fuel prices. Keep in mind, this is just an estimate; your actual fuel costs may vary depending on your driving habits, the type of fuel you use (premium is recommended), and local gasoline prices. If you live in an area with higher fuel costs or tend to drive more aggressively, expect to exceed this figure. It’s wise to factor this cost into your overall budget when considering ownership, alongside insurance, maintenance, and potential repairs. Remember to explore all Lexus fuel economy data.

Real-world expectations

The EPA’s numbers provide a useful baseline, but real-world MPG often differs. Drivers who prioritize smooth acceleration and consistent speeds are more likely to match or even slightly exceed the EPA highway figure. Conversely, frequent bursts of acceleration, extended idling in traffic, and spirited driving in sport mode will significantly reduce fuel economy. Based on owner reports and independent testing, expect a real-world combined MPG in the range of 19-24, depending on your driving style and conditions. It’s also worth remembering that the IS 350 performs best on premium fuel, which adds to the overall cost of ownership.

How it compares

The IS 350 AWD’s fuel economy isn’t exactly class-leading. A comparable BMW 330i xDrive, with its turbocharged four-cylinder engine, achieves a combined 28 MPG. The Acura TLX with SH-AWD and the turbocharged 2.0-liter engine gets around 24 MPG combined. Even the Audi S4, with its significantly more powerful turbocharged V6, manages a respectable 24 MPG combined. However, the IS 350’s naturally aspirated V6 delivers a unique driving experience that some buyers value, prioritizing smooth power delivery and a distinctive engine note over outright efficiency. The availability of IS MPG across all years can also help buyers make key decisions. The IS 350 buyer knows these comparisons full well, but they are choosing a specific kind of character, sound, and feel that these competitors do not offer.

Tips to maximize efficiency

While the IS 350 isn’t designed for hypermiling, there are steps you can take to improve its fuel economy. Avoid aggressive acceleration and braking. The V6 loves to rev, but those quick bursts of power come at a significant cost to efficiency. Drive smoothly and anticipate traffic flow to minimize the need for sudden speed changes.

Ensure your tires are properly inflated. Underinflated tires increase rolling resistance, forcing the engine to work harder and consume more fuel. Check your tire pressures regularly and maintain them at the recommended levels listed on the driver’s side doorjamb.

Reduce unnecessary weight in the vehicle. Hauling around extra cargo adds to the vehicle’s load, decreasing fuel efficiency. Remove any items you don’t need on a regular basis, such as golf clubs, extra tools, or heavy objects in the trunk.

Use cruise control on the highway. Maintaining a constant speed helps to optimize fuel consumption. Engaging cruise control on long, flat stretches of road can make a noticeable difference in your overall MPG.

Consider using the ECO mode in normal driving conditions. This mode adjusts the engine and transmission settings to prioritize fuel efficiency, although it does dull throttle response. Keep in mind the IS 350 is still a performance car, and ECO mode does impact its character and responsiveness.