25 MPG combined might not sound impressive, but for the 2023 Mercedes-Benz CLS450 4matic, it’s a reasonable compromise. This isn’t a hypermiling commuter car; it’s a stylish, luxurious four-door coupe designed for effortless cruising. The target buyer isn’t prioritizing ultimate efficiency. They desire a distinctive vehicle with a potent engine and a premium experience, and they’re willing to accept mid-pack fuel economy.

City and highway performance

The EPA estimates the CLS450 4matic achieves 22 MPG in the city and 30 MPG on the highway. This split reflects the car’s character: smooth and responsive around town thanks to its turbocharged 3.0-liter inline-six engine with mild-hybrid assist, and supremely relaxed on long highway stretches. The 9-speed automatic transmission helps keep the engine in its sweet spot, maximizing efficiency at cruising speeds. Stop-and-go city driving will inevitably lower the MPG figures, but the highway number demonstrates the car’s potential for efficient long-distance travel. Engaging cruise control on the open road makes a difference.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2023 Mercedes-Benz CLS450 4matic at $2,300. This figure is based on driving 15,000 miles per year, using national average fuel prices. Your actual fuel costs will vary depending on your driving habits, where you live, and prevailing gas prices. The $2,300 figure provides a standardized benchmark for comparing the CLS450’s fuel expenses against other vehicles. This is a critical number for buyers who want to compare the running costs against other similar vehicles before reviewing CLS450 MPG across all years.

Real-world expectations

While the EPA estimates provide a useful comparison tool, real-world MPG for the CLS450 4matic is likely to fluctuate. Aggressive driving will reduce that 25 MPG combined figure, while gentle cruising on the highway might raise it. Expect to see numbers in the low 20s for mixed driving, with the potential for achieving the advertised 30 MPG on dedicated highway trips. Factors like tire pressure, ambient temperature, and even the specific grade of gasoline used can influence fuel consumption. Treat the EPA numbers as a guideline, but be prepared for some variation based on your individual driving.

How it compares

The CLS450 4matic competes in a segment where style and luxury often outweigh fuel efficiency. The BMW 840i Gran Coupe xDrive, another stylish four-door coupe, achieves a similar 25 MPG combined. The Audi A7 55 TFSI quattro delivers about 24 MPG combined. The Porsche Panamera, while offering sportier performance, comes in at a lower 21 MPG combined in its base configuration. The CLS450 buyer is likely aware of these alternatives and has accepted that these vehicles all operate within a similar fuel economy bracket. They’ve likely made their decision based on styling, features, and brand preference, understanding that all Mercedes Benz fuel economy data hovers around a similar number.

Tips to maximize efficiency

Use the CLS450’s “Eco” driving mode. This mode softens throttle response, optimizes shift points, and reduces climate control load to prioritize fuel efficiency. It’s a simple way to improve your MPG figures without sacrificing too much performance in everyday driving.

Ensure your tires are properly inflated. Underinflated tires increase rolling resistance, forcing the engine to work harder and consume more fuel. Check your tire pressure regularly and inflate them to the recommended levels, typically found on a sticker inside the driver’s side doorjamb.

Anticipate traffic flow and avoid aggressive acceleration and braking. Smooth driving is key to maximizing fuel economy. By looking ahead and anticipating changes in speed, you can minimize unnecessary energy expenditure and improve your MPG.

Minimize idling. Letting the engine idle wastes fuel. If you’re stopped for more than a minute or two, it’s more efficient to turn off the engine and restart it when you’re ready to go. While fuel is used to restart, the amount is less than what’s burned when idling.

Use cruise control on the highway. Maintaining a consistent speed reduces driver fatigue and helps optimize fuel efficiency. Cruise control minimizes unnecessary speed fluctuations, allowing the engine to operate more efficiently.