23 MPG combined isn’t going to win any awards, but it perfectly encapsulates the 2022 Lexus RX 350’s mission: dependable luxury without drastically departing from the established norm. This isn’t transportation aimed at early adopters; buyers choose the RX 350 for its blend of comfort, reliability, and a consistently pleasant experience. Fuel economy, while important, often takes a back seat to these other considerations.

City and highway performance

The EPA estimates the 2022 Lexus RX 350 achieves 20 MPG in the city and 27 MPG on the highway. The city figure reflects stop-and-go traffic, idling, and lower average speeds. The highway rating, on the other hand, showcases the engine’s efficiency at a steady cruise. Those 27 MPG will likely be easily achievable on long road trips, making this a very comfortable vehicle for racking up the miles. The 3.5L V6 delivers adequate power for merging and passing, but it’s tuned more for refinement than outright acceleration. This translates to smooth, predictable performance that favors relaxed driving over aggressive maneuvers. Ultimately, it’s a powertrain calibrated for consistent, unobtrusive operation.

Annual fuel cost

The EPA estimates an annual fuel cost of $1,900 for the 2022 Lexus RX 350. This figure is based on driving 15,000 miles per year, using a weighted average of 55% city driving and 45% highway driving, at the national average fuel price. While individual costs will vary based on driving habits and local fuel prices, this provides a reasonable baseline for understanding the RX 350’s fuel expenses.

Keep in mind that this is merely an estimate and that changes in driving style or fuel prices could lead to significant differences in the actual cost of ownership.

Real-world expectations

While the EPA provides a standardized testing procedure, real-world MPG often deviates from the official numbers. Factors like driving style, traffic conditions, terrain, and even tire pressure can influence fuel consumption. RX 350 drivers who prioritize smooth acceleration and maintain consistent speeds are likely to see figures closer to the EPA estimates. Aggressive driving, frequent short trips, and hilly terrain will invariably reduce fuel economy.

It’s reasonable to expect a range of 21-25 MPG in combined driving, depending on these variables. Owners who track their fuel consumption using smartphone apps or the vehicle’s trip computer can gain a more accurate understanding of their individual fuel economy performance.

How it compares

The RX 350’s fuel economy sits roughly in the middle of the luxury midsize SUV segment. The Acura MDX with its 3.5L V6 is rated at 22 MPG combined, making it a close competitor. The BMW X5 sDrive40i (RWD) achieves 23 MPG combined, the same as the RX 350, though the all-wheel drive version dips to 21 MPG. A Volvo XC60 B5 manages 25 MPG combined. These competing models often appeal to buyers seeking a comparable blend of luxury, space, and features, making MPG a crucial point of comparison. Lexus also offers a hybrid variant of the RX, the RX 450h, which substantially improves fuel economy, offering an alternative for buyers wanting less gas. You can also look at RX MPG across all years to see historical fuel economy trends. Before making a purchasing decision, be sure to also compare all Lexus fuel economy data.

Tips to maximize efficiency

Gentle acceleration and braking are crucial for maximizing fuel economy in the RX 350. Avoid aggressive starts and hard stops, as these actions consume significantly more fuel. The RX 350’s automatic transmission is programmed to upshift early and downshift smoothly, focusing on efficiency.

Allowing it to manage gear changes without aggressive throttle input will yield better results. Maintaining proper tire pressure is essential. Underinflated tires increase rolling resistance, forcing the engine to work harder and reducing fuel economy. Check your tire pressure regularly and inflate them to the recommended level, which can be found on the driver’s side doorjamb or in the owner’s manual.

Reduce unnecessary weight. Carrying excessive cargo in the RX 350 adds to the vehicle’s overall weight, which decreases fuel efficiency. Remove any items that are not essential for daily use.

Minimize idling time. The RX 350 consumes fuel even when stationary with the engine running. Avoid idling for extended periods, especially in situations like waiting in parking lots or drive-throughs. Turn off the engine if you anticipate a prolonged wait.