25 MPG combined is an acceptable figure for the 2022 Lexus NX 350 AWD, but it’s not going to win any hypermiling contests. This compact luxury SUV prioritizes comfort, technology, and all-weather confidence over outright fuel efficiency, a trade-off that resonates with many buyers in this segment. The NX 350 is for those who appreciate a well-appointed interior, a smooth ride, and the reassurance of all-wheel drive without necessarily chasing the absolute lowest fuel costs.

City and highway performance

The EPA estimates for the 2022 NX 350 AWD break down to 22 MPG in the city and 29 MPG on the highway. The city figure reflects the reality of stop-and-go traffic, where the turbocharged 2.4L engine works harder. The highway number is more encouraging, suggesting that longer journeys at consistent speeds will yield better results. Achieving that 29 MPG will require a light foot and a willingness to let the eight-speed automatic transmission do its job and keep the engine in its most efficient operating range. Some drivers find the NX 350 more rewarding on longer trips than around town, especially when factoring in the comfortable seats and quiet cabin.

Annual fuel cost

The EPA estimates an annual fuel cost of $2,300 for the 2022 Lexus NX 350 AWD. This figure is based on driving 15,000 miles per year and assumes current national average fuel prices. The actual amount you spend on fuel will depend on your individual driving habits, the type of roads you typically drive on, and the prevailing fuel prices in your area. This $2,300 figure provides a useful baseline for comparison against other vehicles, helping you understand the potential long-term running costs of the NX 350.

Real-world expectations

While the EPA provides standardized testing data, real-world fuel economy can vary significantly. Factors like aggressive driving, carrying heavy loads, and using accessories like air conditioning can all reduce MPG. Cold weather can negatively impact fuel economy. Most owners report figures reasonably close to the EPA estimates, suggesting that Lexus has done a good job of translating test results into real-world performance. Checking NX MPG across all years is a good way to spot trends or individual model year issues.

How it compares

The NX 350 AWD’s 25 MPG combined puts it in the middle of the pack compared to its competitors. The Acura RDX, for example, is EPA-rated at 23 MPG combined, making the Lexus a slightly more frugal choice. The BMW X3 xDrive30i, another popular option, also achieves around 24-25 MPG combined. A Mercedes-Benz GLC 300 4MATIC isn’t much better either, achieving around 25 MPG combined. Stepping up to a hybrid version like the NX 350h (rated at 39 MPG combined) or a plug-in hybrid like the NX 450h+ (84 MPGe combined) offers a significant efficiency boost, but comes at a higher price point. For buyers prioritizing all Lexus fuel economy data with a traditional gasoline engine and AWD, the NX 350 represents an acceptable balance of performance and economy.

Tips to maximize efficiency

Gentle acceleration is key to maximizing fuel economy in the NX 350. The turbocharged engine delivers ample power, but using it sparingly will reduce fuel consumption. Avoid aggressive starts and maintain a steady speed whenever possible.

Monitor your tire pressure regularly. Underinflated tires increase rolling resistance and reduce fuel efficiency. Consult the sticker on the driver’s side doorjamb for the recommended tire pressure and use a tire pressure gauge to check your tires at least once a month.

Reduce unnecessary weight. Carrying extra cargo in the vehicle adds to its overall weight, which negatively impacts fuel economy. Remove any items you don’t need to carry on a regular basis.

Plan your trips strategically. Combining errands into a single trip will reduce the amount of time spent driving with a cold engine, which is less fuel-efficient. Consider using a route planner to avoid traffic congestion and find the most efficient route.

Use the drive mode selector. The NX 350 offers different drive modes, such as Eco, Normal, and Sport. Selecting “Eco” mode can optimize various vehicle settings for improved fuel efficiency, although it may slightly reduce throttle response.