Lexus · 2022
ES 350 F Sport 3.5L 6-cyl
✓ EPA Verified
Regular Gasoline
Midsize Cars
Front-Wheel Drive
City
22
MPG
Combined
25
MPG
Highway
31
MPG
Annual Fuel Cost
$1,750
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$400
saved per year
Class Comparison — Midsize Cars
Bottom 35%
Better than 35 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 25 MPG
This vehicle
25 MPG
Class average
35 MPG
Class lowest
13 MPG
EPA Energy & Environment Scores
5
Energy Score
Out of 10
5
GHG Score
Out of 10
352 lbs
Annual CO₂
g/mile tailpipe CO₂
No
Start-Stop
Not equipped
Vehicle Specifications
Engine3.5L 6-cyl
TransmissionAutomatic (S8)
DriveFront-Wheel Drive
Fuel TypeRegular Gasoline
Vehicle ClassMidsize Cars
Engine DescSIDI & PFI
Start-StopNo
EPA Vehicle ID44455

The 2022 Lexus ES 350 F Sport’s 25 MPG combined fuel economy won’t top any lists. However, it provides acceptable gas mileage for a strong V6-powered luxury sedan, prized for its comfortable ride, refined interior, and unwavering reliability. Buyers who prioritize driving pleasure above all else might find the ES 350 F Sport lacking in outright athleticism. But the target consumer, professionals and empty-nesters seeking a luxurious and dependable daily driver, find that the ES offers a pleasing mix of power and refinement, without using gas at an embarrassing rate.

City and highway performance

The EPA estimates 22 MPG in the city and 31 MPG on the highway for the 2022 Lexus ES 350 F Sport. These figures reflect various driving conditions and contribute to the combined 25 MPG rating. The highway number is particularly relevant because many ES owners use their vehicles for longer commutes and road trips. The eight-speed automatic transmission helps, keeping the engine in its most efficient range at cruising speeds. In city driving, the smooth and responsive 3.5-liter V6 makes navigating traffic easy, even if the fuel economy declines slightly compared to highway performance.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2022 Lexus ES 350 F Sport at $1,750. This is based on driving 15,000 miles per year and national average fuel prices. This is just an estimate; your actual fuel costs will vary based on your driving habits, local fuel prices, and the type of fuel you use. Still, $1,750 provides a useful benchmark when comparing the ES 350 F Sport’s running costs to other vehicles.

Real-world expectations

The EPA estimates provide a standard for comparison, but real-world fuel economy can vary greatly. Aggressive driving, frequent short trips, and prolonged idling can all hurt efficiency. However, gentle acceleration, consistent highway speeds, and proper tire inflation can help you get the EPA estimates or even exceed them. Expect numbers close to the EPA’s, but where and how you drive the vehicle can cause variance.

How it compares

The Lexus ES 350 F Sport faces competition from other mid-size luxury sedans. For example, the Acura TLX, with its standard 2.0-liter turbo engine, gets around 24 MPG combined, a little less than the ES 350 F Sport. The Volvo S60 B5 FWD, with its mild-hybrid engine, achieves approximately 29 MPG combined, which gives it an edge in fuel efficiency. S60 buyers might prioritize its Scandinavian design and available all-wheel drive over the ES’s reputation for strong reliability. The BMW 530i, rated at 28 MPG combined, provides a sportier driving experience but usually costs more. These comparisons indicate that fuel economy is just one factor, and buyers often balance it against performance, features, and brand. You can view all Lexus fuel economy data to see how the ES compares to other models, and learn more about ES MPG across all years.

Tips to maximize efficiency

The Lexus ES 350 F Sport’s V6 works well with a smooth, steady driving style. Avoid quick acceleration and hard braking because they consume more fuel. Watch traffic flow and keep a consistent speed.

Regular maintenance is important for fuel economy. Ensure your tires have the recommended pressure because underinflated tires increase rolling resistance and cut efficiency. Also, keep up with scheduled oil changes.

Keep idling time short. If you’re stopped for more than a minute, turn off the engine. Modern engines restart quickly, and idling wastes fuel.

Use the ES 350 F Sport’s drive modes carefully. Sport mode improves throttle response and steering feel, but it also consumes more fuel. For daily driving, use Eco mode to increase fuel efficiency.

Reduce weight in the vehicle. Extra cargo adds to the weight, which can lower fuel economy. Remove items that are not needed.