22 MPG combined isn’t going to win the 2022 Honda Odyssey any awards, but it’s an acceptable sacrifice for the minivan’s unparalleled practicality and family-hauling capabilities. This isn’t a vehicle designed for solo commutes or weekend joyrides, it’s a purpose-built machine engineered to conquer school carpools, family road trips, and the endless logistical challenges of modern parenthood. Odyssey buyers understand this trade-off, prioritizing space, comfort, and reliability over Prius-like fuel efficiency.

City and highway performance

The Odyssey’s EPA ratings break down to 19 MPG in the city and 28 MPG on the highway. The city figure reflects the stop-and-go nature of urban driving, where the Odyssey’s 3.5L V6 works harder to accelerate its considerable weight. Highway driving, however, allows the engine to settle into a more efficient cruise, aided by the smooth-shifting 10-speed automatic transmission. That transmission (designated “S10” by the EPA) definitely matters here, older Odysseys with 6- and 9-speed automatics show different results. It’s important to know that the EPA numbers reflect the *potential* of vehicles, and drivers can consult ODYSSEY MPG across all years to compare.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2022 Honda Odyssey at $2,000. This figure is based on driving 15,000 miles per year and using national average fuel prices. Of course, your actual fuel costs will vary based on your driving habits, the type of roads you drive on, and the price of gasoline in your area.

Real-world expectations

While the EPA numbers provide a standardized benchmark, real-world fuel economy often deviates. Odyssey drivers who frequently encounter heavy traffic or have a lead foot may see figures closer to the city rating, while those who primarily drive on the highway can realistically achieve numbers at or even slightly above the EPA’s 28 MPG estimate.

Regular maintenance, including proper tire inflation and timely oil changes, can also positively impact fuel efficiency.

How it compares

The Toyota Sienna, with its standard hybrid powertrain, significantly outperforms the Odyssey with a combined 36 MPG. That’s a huge consideration for eco-minded buyers, and something that many Odyssey owners eye with envy. However, the Chrysler Pacifica Hybrid, another plug-in option, gets 32 MPG combined (520 miles total range) when operating as a hybrid, though that number changes depending on how diligently you approach charging. The gasoline-only Pacifica is rated at 22 MPG combined, matching the Odyssey. KIA’s Carnival slides in with ratings close to other vans, its EPA ratings are 19 city / 26 highway / 22 combined. While the Odyssey doesn’t lead the pack in fuel economy, its spacious interior, reputation for reliability, and well-rounded driving experience continue to make it a popular choice for families, even if they have to plan for slightly more frequent trips to the gas station. View all Honda fuel economy data to consider other options.

Tips to maximize efficiency

Anticipate traffic flow and avoid abrupt acceleration and braking. The Odyssey’s smooth V6 responds well to a gentle touch, and maintaining a consistent speed will significantly improve your fuel economy. Remember heavier acceleration burns more gas.

Keep your tires properly inflated to the recommended pressure. Underinflated tires increase rolling resistance, forcing the engine to work harder and burning fuel unnecessarily. Check your tire pressure regularly, especially during temperature changes.

Minimize the amount of weight you carry in the Odyssey. The less weight the engine has to move, the better your fuel economy will be. Remove unnecessary items from the cargo area and consider removing the removable second-row seats if you don’t regularly need them.

Use the Odyssey’s cruise control feature on the highway. This helps maintain a constant speed, further optimizing fuel efficiency on long trips. Also, modern cruise control systems are smart; they will automatically adjust to elevation changes and headwind/tailwind situations to keep you in the most fuel-efficient driving position.

Consider using a fuel additive designed to clean fuel injectors. Over time, deposits can build up in the fuel injectors, reducing their efficiency and negatively impacting fuel economy. Fuel injector cleaners can help remove these deposits and restore optimal performance. These can be purchased at any auto parts store.