15 MPG combined isn’t likely to impress Prius drivers. But that’s what the 2021 Toyota Sequoia 2WD with the 5.7L V8 gets, and it accurately reflects what this vehicle is: a body-on-frame, truck-based SUV with seating for up to eight, serious towing capacity, and a reputation for Toyota reliability. Buyers needing what the Sequoia offers and those prioritizing fuel efficiency are usually looking for different things.

City and highway performance

The EPA estimates for the 2021 Sequoia 2WD 5.7L are 13 MPG in the city and 17 MPG on the highway. These figures show the penalty for moving nearly three tons with a naturally aspirated V8. The city figure shows the impact of stop-and-go traffic on a large engine. The highway figure is slightly better, mainly because the engine is at a steady state more of the time, and the six-speed automatic transmission is in its highest gear. It’s a trade-off Sequoia buyers willingly accept for the vehicle’s capabilities and expected lifespan.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2021 Toyota Sequoia 2WD 5.7L at $2,900. This is based on driving 15,000 miles per year, with 55% of those miles in the city and 45% on the highway, using national average fuel prices. This is just an estimate. Actual fuel costs will vary depending on driving habits, local fuel prices, and driving type. If you’re using your Sequoia for towing or frequently driving in low-traction situations, expect that $2,900 figure to increase. The Sequoia is for those who appreciate the power and dependability of a proven powertrain.

Real-world expectations

The EPA provides a benchmark, but real-world fuel economy often differs. Sequoia owners frequently report figures close to the EPA estimates, especially on longer highway drives. Aggressive acceleration, heavy loads, and accessories like roof racks can hurt MPG. Driving gently, inflating the tires properly, and doing regular maintenance can help you stay closer to the advertised numbers. The Sequoia’s size and weight mean that even small changes in driving style can create noticeable differences in fuel consumption. Those thinking about buying should browse owner forums dedicated to the Sequoia to understand what to expect behind the wheel.

How it compares

The 2021 Sequoia is in a segment of large, truck-based SUVs where MPG is secondary to capability. The Chevrolet Tahoe delivers fuel economy in the mid-teens, with a combined EPA rating of around 17 MPG for the 2WD 5.3L V8 model. A Ford Expedition with the 3.5L EcoBoost engine can get slightly better figures, typically in the 17-19 MPG combined range, though real-world numbers often get closer when towing. The Nissan Armada posts EPA numbers similar to the Sequoia. Choosing a Sequoia is often about Toyota’s reliability, perceived quality, and the truck’s reputation. For specific details, see SEQUOIA MPG across all years.

Tips to maximize efficiency

The Sequoia isn’t particularly fuel-efficient, but certain habits can help. Avoid aggressive acceleration and hard braking, because the Sequoia’s weight means that accelerating quickly requires a lot of fuel. Smooth acceleration will reduce fuel usage.

Maintain proper tire inflation; under-inflated tires create more rolling resistance, forcing the engine to work harder. Check your tire pressure regularly and inflate them to the manufacturer’s recommended specifications listed on the driver’s side door jamb. Your tires should also be suited for the heavy-duty driving for which you bought the Sequoia.

Reduce weight whenever possible; carrying heavy cargo increases the engine’s workload and reduces fuel economy. Remove unnecessary items from the vehicle, especially when not towing. Keeping the cabin as light as possible helps fuel economy.

Service the 5.7L V8 on schedule. A maintained engine runs more efficiently. Make sure that oil changes, air filter replacements, and spark plug replacements are done on time. Maintenance will help to ensure performance and fuel economy that fits the all Toyota fuel economy data.

Limit idling time; idling consumes fuel without covering any distance. If you anticipate stopping for several minutes, it’s more fuel-efficient to turn off the engine, especially with a large engine.