22 MPG combined is almost irrelevant for the 2021 Porsche Panamera 4S e-Hybrid. This isn’t a car driven by hypermilers. It’s a four-door luxury performance car with a plug, bought by people who prioritize exhilarating power and distinctive style over squeezing every last mile from a gallon of premium. Fuel economy is a consideration, but a secondary one to the overall experience.

City and highway performance

The EPA estimates the Panamera 4S e-Hybrid at 21 MPG in the city and 23 MPG on the highway. These figures reflect the typical blend of gasoline and electric propulsion in real-world driving. Porsche’s hybrid system blends the 2.9L twin-turbo V6 with its electric motor, prioritizing electric range when available but instantly delivering the combined power of both when you demand it. In purely electric mode, you can expect to cover a limited range on a full charge, perfect for shorter commutes or errands. The versatility of the e-Hybrid is that you can enjoy quiet, emissions-free driving when possible, while always having the V6’s substantial power in reserve.

Annual fuel cost

According to the EPA, the annual fuel cost for the 2021 Porsche Panamera 4S e-Hybrid is $2,650. This figure is based on driving 15,000 miles per year, with a predetermined percentage split between city and highway miles, and using the national average fuel price for premium gasoline at the time of calculation. Your actual fuel cost will vary depending on your driving habits, the price of gasoline in your area, and how frequently you use the plug-in charging capability. If you’re diligent about plugging in and primarily use the car for shorter trips, you’ll likely spend significantly less than $2,650 annually. If you treat the electric motor purely as a performance enhancer and drive primarily on the highway, expect to exceed it. Find PANAMERA MPG across all years on this site.

Real-world expectations

While the EPA numbers provide a baseline, real-world fuel economy for the Panamera 4S e-Hybrid depends on driving style and charging habits. Owners who plug in often and prioritize electric driving can easily achieve much higher average MPG figures, especially during shorter commutes. However, those who frequently exploit the car’s performance potential and neglect charging will likely see numbers closer to, or even below, the EPA estimates. The on-board trip computer is your best tool for monitoring your own fuel consumption and adjusting your driving behavior accordingly. Understanding how the electric motor and gasoline engine interact is critical to maximizing efficiency.

How it compares

The 2021 Panamera 4S e-Hybrid sits in a unique segment, balancing performance and a degree of electrification. A direct comparison is difficult, but let’s examine some alternatives. The BMW 745e xDrive, another plug-in hybrid luxury sedan, achieves a combined 22 MPG, similar to the Panamera, while offering a different driving experience. The Mercedes-Benz S560e (prior to its redesign) offered similar plug-in hybrid capability but has since changed. Traditional gasoline-powered competitors, such as the Audi S7 (rated at 22 MPG combined), offer comparable fuel economy without the electric assist, but lack the potential for all-electric driving. For the Panamera 4S e-Hybrid buyer, the comparison isn’t solely about MPG numbers; it’s about the blend of performance, luxury, and lower fuel costs. Many of these same buyers might also be curious about all Porsche fuel economy data, including the all-electric Taycan.

Tips to maximize efficiency

Charge whenever possible. Even short top-ups can significantly increase your electric driving range and reduce your reliance on the gasoline engine. Use a Level 2 charger at home for faster charging times.

Use the Panamera’s various driving modes. The “E-Power” mode maximizes electric driving, while “Hybrid Auto” intelligently manages the blend of electric and gasoline power for optimal efficiency. “Sport” and “Sport Plus” modes prioritize performance and will significantly reduce fuel economy.

Anticipate traffic flow and avoid aggressive acceleration and braking. Smooth, consistent driving maximizes efficiency in both electric and gasoline modes. Regenerative braking helps recapture energy and recharge the battery, extending your electric range.

Pay attention to tire pressure. Properly inflated tires reduce rolling resistance and improve fuel economy. Consult the sticker on your driver’s side doorjamb for the recommended tire pressure.

Minimize accessory usage. Air conditioning and other power-draining accessories increase energy consumption and reduce electric range. Use them carefully, especially when driving in electric mode.