The 2021 Mercedes-Benz S580 4matic gets 20 MPG combined, which isn’t winning any awards for fuel efficiency, but that’s not the main goal of this exceptional machine. This is a flagship sedan, a clear sign of success, and its fuel consumption is likely a secondary concern for the wealthy buyer who values effortless power, advanced technology, and unmatched luxury. This vehicle shows the best of Mercedes-Benz engineering, a fact showcased by its presence on the road and the quality of its interior.

City and highway performance

The S580’s 4.0L twin-turbo V8 engine uses fuel quickly, mostly in stop-and-go city driving. The EPA rates it at 17 MPG in the city, a number that’s not surprising for a vehicle of this size and weight. However, on the open highway, the S580 performs better, achieving 25 MPG. The smooth-shifting 9-speed automatic transmission optimizes fuel efficiency at higher speeds, letting the engine cruise comfortably in its most efficient range. Drivers who often take long trips will likely find the highway MPG more acceptable than the city MPG.

Annual fuel cost

According to the EPA, the estimated annual fuel cost for the 2021 Mercedes-Benz S580 4matic is $2,900. This calculation is based on driving 15,000 miles per year, using national average fuel prices. Actual fuel costs will vary depending on driving habits, local fuel prices, and the type of fuel used. Premium fuel is recommended for best performance, which increases the overall cost. Consider this figure a guide; your personal expenses could be higher or lower depending on your circumstances.

Real-world expectations

While the EPA estimates provide a starting point, real-world fuel economy can change. Fast acceleration, frequent short trips, and long idling times will reduce fuel efficiency. Gentle driving, steady highway speeds, and proper vehicle maintenance can help improve it. Some owners report fuel economy within the EPA range but acknowledge that spirited driving can easily drop the MPG below the stated figures. The S580 rewards conservative driving, but the temptation of its power might lead you to enjoy some quick acceleration, which will consume more fuel.

How it compares

Among flagship luxury sedans with powerful engines, the S580’s fuel economy is similar to its competitors. The BMW 750i xDrive, with its 4.4L V8, gets about 17 MPG city and 25 MPG highway. The Audi A8, offers a more fuel-efficient plug-in hybrid version, but the standard V6 engine gets around 19 MPG combined. The Lexus LS 500, known for reliability, achieves 19 MPG city and 30 MPG highway, but it does not have the same level of power as the S580’s twin-turbo V8. These comparisons are important to buyers who want reasonable gas mileage for their class of vehicle, even if fuel efficiency isn’t their top priority. You can review all Mercedes Benz fuel economy data to put this model into context.

Tips to maximize efficiency

The S580’s all-wheel-drive system improves traction and handling, but adds weight and complexity, slightly reducing fuel efficiency. Drive smoothly, avoid unnecessary hard acceleration and let the turbochargers build power gradually rather than quickly. Anticipate traffic to reduce braking and keep a consistent speed, especially on the highway.

Engage the “Eco” driving mode, if the vehicle has it. This mode adjusts the engine and transmission for better fuel economy, often resulting in a softer throttle response and earlier upshifts. This mode can reduce overall performance; use it mainly when efficiency is important.

Make sure the tires are properly inflated and kept at the recommended pressure. Underinflated tires increase rolling resistance, leading to lower fuel economy. Check tire pressure regularly and inflate when needed to the specified level.

Reduce the of auxiliary systems like air conditioning and heated seats. These features use power from the engine, increasing fuel use. Only use them when needed to stay comfortable. If possible, use natural ventilation or wear layers of clothing to adjust temperature.

Remove unnecessary weight from the vehicle. Extra cargo in the trunk or rear seats adds to the overall load, making the engine work harder and use more fuel. Keeping the vehicle clear can contribute to small, yet noticeable, improvements in fuel economy. Looking at S580 MPG across all years may also be enlightening.