23 MPG combined in the 2021 Mercedes-Benz GLE450 4matic is a respectable figure for a mid-size luxury SUV with a turbocharged 3.0L inline-six and all-wheel drive. This isn’t a vehicle purchased for prioritizing fuel consumption; it’s for buyers seeking a confident, refined driving experience with ample space and a prestigious badge. Fuel economy is a consideration, but performance, technology, and comfort are the priority.

City and highway performance

The EPA estimates for the GLE450 are 21 MPG in the city and 26 MPG on the highway. The city number reflects the stop-and-go realities of urban commutes, where the GLE450’s weight and turbocharger lag can impact efficiency. The highway figure is better, thanks to the smooth-shifting 9-speed automatic transmission that allows the engine to cruise at low RPMs. The tall gearing helps conserve fuel on long journeys, making the GLE450 a competent road trip vehicle despite its lower city MPG.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2021 Mercedes-Benz GLE450 4matic at $2,500. This is based on driving 15,000 miles per year and using national average fuel prices. Your individual costs will vary depending on driving habits, local fuel prices, and the type of fuel used. More aggressive driving or pricier premium fuel will increase that amount, so consider your own driving circumstances to assess your real yearly cost.

Real-world expectations

EPA numbers are just that, numbers. Your GLE450 MPG will vary based on several factors. Driving style is a major contributor, lead-footed drivers will see significantly lower numbers. Those with a gentler touch might match or exceed the EPA estimates. Terrain also plays a role, hilly areas decrease fuel economy. Remember the impact of accessories and cargo as well. A roof rack or a loaded cargo area will reduce aerodynamic efficiency and increase weight, lowering your mileage.

How it compares

The GLE450 is in a competitive segment where fuel efficiency varies. The BMW X5 xDrive40i, with its similar six-cylinder engine and all-wheel drive, gets a comparable 23 MPG combined. The Volvo XC90 B6 AWD gets a slightly better 22 MPG combined despite all-wheel drive and a turbocharged and supercharged engine. The Audi Q7 55 TFSI offers a similar level of luxury and performance but gets only 20 MPG combined. This difference matters to buyers who are cross-shopping for the right blend of luxury, capability, and fuel efficiency among these SUVs. Comparing GLE450 MPG across all years can also provide context.

Tips to maximize efficiency

Use the GLE450’s ECO driving mode. This setting optimizes the engine and transmission for fuel efficiency, resulting in improvements, especially in city driving. Use it, even if it slightly reduces throttle response.

Make sure your tires are inflated to the recommended pressure. Underinflated tires increase rolling resistance, which reduces fuel economy. Check your tire pressure regularly, especially during temperature changes.

Minimize idling. Modern cars, including the GLE450, consume fuel even when stationary with the engine running. If you’re stopped for more than a minute, turn off the engine.

Reduce excess weight. Extra cargo adds to the vehicle’s weight, impacting fuel efficiency. Clearing out unneeded items from the trunk or cargo area can make a difference. You can browse all Mercedes Benz fuel economy data to see how other models compare.