Mercedes-Benz · 2021
C300 4matic 2.0L 4-cyl
✓ EPA Verified
Premium Gasoline
Compact Cars
4-Wheel Drive
City
23
MPG
Combined
27
MPG
Highway
33
MPG
Annual Fuel Cost
$2,150
Based on 15,000 miles/year · EPA estimates
Class Comparison — Compact Cars
Bottom 45%
Better than 45 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 27 MPG
This vehicle
27 MPG
Class average
33 MPG
Class lowest
12 MPG
EPA Energy & Environment Scores
6
Energy Score
Out of 10
6
GHG Score
Out of 10
329 lbs
Annual CO₂
g/mile tailpipe CO₂
Yes
Start-Stop
Auto stop-start
Vehicle Specifications
Engine2.0L 4-cyl
TransmissionAutomatic 9-spd
Drive4-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassCompact Cars
Engine DescSIDI
Start-StopYes
EPA Vehicle ID43348

27 MPG combined. That’s the key fuel economy figure for the 2021 Mercedes-Benz C300 4matic, reflecting a compromise between performance, luxury, all-weather capability and fuel consumption. This isn’t a hybrid, and it’s not for buyers seeking ultimate efficiency. It’s a stylish sedan for drivers who value the Mercedes star and accept the fuel needs as part of owning one. They want a smooth ride, a well-appointed interior, and all-wheel drive, even if it means stopping for gas more often than a Prius owner.

city and highway performance

The EPA estimates 23 MPG in the city and 33 MPG on the highway for the 2021 C300 4matic. These numbers show the powertrain’s strengths and weaknesses. The turbocharged 2.0L four-cylinder engine works harder in stop-and-go traffic, resulting in the lower city MPG. The C300 is most efficient when cruising on the open road, because the smooth-shifting 9-speed automatic transmission allows the engine to run at a more economical rpm. The highway number is competitive within its class, suggesting that long road trips in the C300 won’t be too expensive.

annual fuel cost

The EPA estimates the annual fuel cost for the 2021 Mercedes-Benz C300 4matic at $2,150. This is based on driving 15,000 miles per year and national average fuel prices. This is just an estimate, and your actual fuel costs can change depending on your driving, local fuel prices, and the type of fuel you use. Premium fuel is recommended for this vehicle, which could increase your annual cost.

real-world expectations

The EPA provides standardized testing data; however, real-world fuel economy can vary. Some C300 owners report numbers close to the EPA figures, especially with careful driving. Aggressive acceleration, frequent short trips, and heavy city driving will lower fuel efficiency. The 4matic all-wheel-drive system adds weight and drivetrain friction, which can hurt MPG compared to a rear-wheel-drive model. Checking C300 MPG across all years and reading owner forums can offer insight into realistic expectations.

how it compares

The C300 4matic is in a segment with fuel-efficient alternatives. The BMW 330i xDrive gets a similar 28 MPG combined, with performance and efficiency. The Audi A4 Quattro gets around 27 MPG combined, close to the C300. The Lexus IS 350 AWD has more horsepower, but its fuel economy is lower at around 22 MPG combined. These differences matter to buyers comparing these vehicles. A buyer focused on less gas might look at a hybrid like the Lexus ES 300h, which boasts 44 MPG combined, with a different driving feel. Viewing all Mercedes Benz fuel economy data can help you compare your specific needs.

tips to maximize efficiency

Use the C300’s driving modes. Select “Eco” mode when performance isn’t important, like highway cruising or gentle city driving. This mode adjusts throttle response and shift points to make the car more fuel efficient.

Keep tires properly inflated. Underinflated tires increase rolling resistance, which reduces fuel economy. Check your tire pressure often and inflate them to the recommended pressure on the driver’s side doorjamb. A tire pressure gauge is a useful tool for any C300 owner.

Avoid aggressive driving. Fast acceleration, hard braking, and speeding use more gas. Smooth driving will increase your MPG. Watch traffic and maintain a steady pace.

Don’t idle. Letting your engine idle uses fuel. If you’re stopped for more than a minute, it’s more fuel-efficient to turn off the engine and restart it. The C300’s engine start/stop system can do this automatically in many cases.

Keep your vehicle maintained. Regular maintenance, including oil changes, air filter replacements, and tune-ups, helps your engine run well. Follow the manufacturer’s maintenance schedule to keep your C300 in good condition and use less gas.