Lexus · 2021
RX 350 L 3.5L 6-cyl
✓ EPA Verified
Regular Gasoline
Small Sport Utility Vehicle 2WD
Front-Wheel Drive
City
19
MPG
Combined
22
MPG
Highway
26
MPG
Annual Fuel Cost
$2,000
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$150
saved per year
Class Comparison — Small Sport Utility Vehicle 2WD
Bottom 8%
Better than 8 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 22 MPG
This vehicle
22 MPG
Class average
37 MPG
Class lowest
18 MPG
EPA Energy & Environment Scores
4
Energy Score
Out of 10
4
GHG Score
Out of 10
407 lbs
Annual CO₂
g/mile tailpipe CO₂
No
Start-Stop
Not equipped
Vehicle Specifications
Engine3.5L 6-cyl
TransmissionAutomatic (S8)
DriveFront-Wheel Drive
Fuel TypeRegular Gasoline
Vehicle ClassSmall Sport Utility Vehicle 2WD
Engine DescSIDI & PFI
Start-StopNo
EPA Vehicle ID42958

The 2021 Lexus RX 350 L owners average 22 MPG combined, a figure that probably isn’t the primary concern for buyers wanting a comfortable and reliable three-row luxury SUV. The RX 350 L provides occasional extra seats in a package that’s smaller than a full-size SUV, and it does so with Lexus’s strong reputation for dependability. While there are more fuel-efficient choices, the RX 350 L appeals to buyers who value its unique blend of traits.

City and highway performance

The RX 350 L gets 19 MPG in the city and 26 MPG on the highway. The city figure reflects the RX 350 L’s weight and the inefficiencies of stop-and-go driving. The highway number is more respectable, indicating the 3.5L V6 and 8-speed automatic transmission are reasonably efficient when cruising at a steady speed. However, even on the highway, the aerodynamics of a three-row crossover hurt fuel consumption.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2021 Lexus RX 350 L at $2,000. This is based on driving 15,000 miles per year and national average fuel prices. More driving, aggressive driving, and higher fuel prices could increase this cost. This provides a benchmark for comparing the RX 350 L to other vehicles, but individual fuel costs will vary.

Real-world expectations

While the EPA estimates are a good baseline, real-world MPG can vary. Driving style, traffic, and tire pressure can affect fuel economy. Owners who primarily drive in heavy traffic will likely see numbers closer to the city estimate, while those who do mostly highway driving might approach or slightly exceed the highway figure. Careful driving can also lead to superior range. Always consult RX MPG across all years to see how different model years compare.

How it compares

The RX 350 L isn’t a leader in fuel economy. Consider the Acura MDX, which achieves 19 MPG city, 26 MPG highway, and 22 MPG combined with its standard engine, matching the RX 350 L. A Volvo XC90 B5, on the other hand, manages 22 MPG city, 29 MPG highway, and 25 MPG combined with its turbocharged and supercharged engine, showing that it uses less gas. Even the Infiniti QX60 with front-wheel drive is rated at 21 MPG city, 28 MPG highway, and 24 MPG combined.

These comparisons show that more fuel-efficient three-row luxury SUVs can be found, but the RX 350 L’s target buyer often wants Lexus’s proven reliability and resale value more than peak MPG figures. More all Lexus fuel economy data is available to further inform purchase decisions.

Tips to maximize efficiency

Gentle acceleration is key to maximizing the RX 350 L’s fuel economy. Avoid aggressive starts and hard braking, as these burn extra fuel. Instead, anticipate traffic flow and maintain a smooth, consistent speed whenever possible. The RX 350 L’s 3.5L V6 provides ample power, so there’s no need to step on the gas more than needed.

Proper tire inflation is critical for fuel efficiency. Check your tires regularly and maintain the recommended pressure listed on the driver’s side doorjamb. Underinflated tires increase rolling resistance, which makes the engine work harder and consume more fuel. Plus, properly inflated tires will wear more evenly and last longer.

Reduce weight in the vehicle to improve MPG. The heavier the load, the more fuel the engine needs to burn. Remove any unnecessary items from the trunk or cargo area. Even seemingly small weight increases add up over time.

Consider using the RX 350 L’s Eco mode for routine driving. This mode adjusts the engine mapping and transmission shift points to prioritize fuel efficiency over performance. While performance may decrease slightly, the fuel savings can be worthwhile, especially during city driving. Switching from Eco mode to Normal mode can be done easily.