22 MPG combined defines the 2021 Lexus LS 500 not as a fuel-sipping hybrid, but as a luxury flagship prioritizing a refined driving experience over outright efficiency. This figure is the cost of admission for those seeking the LS’s distinctive blend of opulent comfort, advanced technology, and smooth, powerful performance from its twin-turbocharged V6 engine.

City and highway performance

The LS 500’s EPA ratings break down to 18 MPG in the city and 29 MPG on the highway. The city mileage reflects the demands of stop-and-go traffic, where the engine’s turbos are frequently spooled and the car’s considerable weight comes into play. The highway figure is more respectable, showcasing the engine’s ability to cruise efficiently once up to speed, aided by the smooth-shifting 10-speed automatic transmission. While 29 MPG is reasonable for a large sedan, it’s unlikely to be the determining factor for most LS buyers, who prioritize effortless power and a quiet, comfortable ride during long journeys.

Annual fuel cost

According to the EPA, the annual fuel cost for the 2021 Lexus LS 500 is estimated at $2,650. This estimate is based on driving 15,000 miles per year and using national average fuel prices. Individual fuel costs can vary depending on driving habits, local fuel prices, and the type of fuel used. While this likely isn’t a sticking point for the typical LS buyer, keeping this number in mind can help factor fuel expenses into the overall cost of ownership.

Real-world expectations

While the EPA ratings provide a useful baseline, real-world fuel economy can vary. Drivers with a heavy foot or those who primarily drive in congested city environments are likely to see figures lower than the EPA estimates. Conversely, drivers who spend a significant portion of their time on the highway, maintaining a steady speed, might achieve slightly better fuel economy. The LS MPG across all years demonstrates a consistent focus on luxury and performance rather than segment-leading efficiency.

How it compares

Compared to its competitors, the LS 500 occupies a space reflecting its priorities. The BMW 740i, with its 3.0L turbocharged inline-six, achieves a slightly better 25 MPG combined. The Mercedes-Benz S500, also equipped with a turbocharged inline-six, boasts a similar 24 MPG combined. The Audi A8, with its mild-hybrid V6, lands around 23 MPG combined. These differences, while present, are often negligible for the target demographic. Most buyers in this segment prioritize factors like brand prestige, interior appointments, and ride quality over marginal gains in fuel efficiency. For a broader look at all Lexus fuel economy data, consider exploring information across the lineup.

Tips to maximize efficiency

Use the LS 500’s “Eco” mode, which adjusts throttle response and climate control settings to prioritize fuel efficiency. While it slightly reduces responsiveness, it can help you save fuel during everyday driving, especially in stop-and-go conditions. Don’t constantly accelerate aggressively, as the turbochargers contribute significantly to fuel consumption when frequently spooled.

Ensure your tires are properly inflated to the recommended pressure. Underinflated tires increase rolling resistance, which negatively impacts fuel economy. Check your tire pressure regularly, especially during temperature changes, as pressure can fluctuate.

Minimize idling. If you’re stopped for more than a minute, it’s generally more fuel-efficient to turn off the engine. The LS 500’s smooth and quiet engine start-up makes this a process.

Regular maintenance is key to optimal fuel economy. Ensure that your LS 500 receives regular oil changes, air filter replacements, and routine tune-ups. A well-maintained engine runs more efficiently, contributing to better fuel mileage.