Mercedes-Benz · 2020
CLS450 3.0L 6-cyl
✓ EPA Verified
Premium Gasoline
Compact Cars
Rear-Wheel Drive
City
24
MPG
Combined
26
MPG
Highway
31
MPG
Annual Fuel Cost
$2,250
Based on 15,000 miles/year · EPA estimates
vs avg gas vehicle
$100
more per year
Class Comparison — Compact Cars
Bottom 41%
Better than 41 out of 100 vehicles in its class for fuel efficiency.
This vehicle: 26 MPG
This vehicle
26 MPG
Class average
33 MPG
Class lowest
12 MPG
EPA Energy & Environment Scores
5
Energy Score
Out of 10
5
GHG Score
Out of 10
334 lbs
Annual CO₂
g/mile tailpipe CO₂
Yes
Start-Stop
Auto stop-start
Vehicle Specifications
Engine3.0L 6-cyl
TransmissionAutomatic 9-spd
DriveRear-Wheel Drive
Fuel TypePremium Gasoline
Vehicle ClassCompact Cars
TrimHybrid
Engine DescSIDI; Mild Hybrid
Start-StopYes
EPA Vehicle ID41713

The 2020 Mercedes-Benz CLS450, with its combined fuel economy of 26 MPG, blends sleek four-door coupe styling and a strong engine with respectable efficiency. This isn’t a hyper-efficient hybrid, but it’s a reasonable compromise for buyers who prioritize performance, luxury, and head-turning design over outright fuel savings. The CLS450 attracts individuals who appreciate the finer things and are willing to accept slightly higher fuel costs for a more engaging driving experience.

City and highway performance

The EPA estimates the CLS450 achieves 24 MPG in the city and 31 MPG on the highway. These figures reflect the car’s responsiveness in urban environments and its ability to cruise comfortably on long journeys. The 3.0L inline-six engine, boosted by a mild-hybrid system, delivers ample power for confident acceleration and passing, even at highway speeds. The nine-speed automatic transmission helps fuel efficiency by keeping the engine in its optimal rev range. The relatively small difference between city and highway MPG reflects a well-optimized powertrain that performs consistently across different driving scenarios.

Annual fuel cost

The EPA estimates the annual fuel cost for the 2020 Mercedes-Benz CLS450 at $2,250. This figure is based on driving 15,000 miles per year and using the national average fuel price at the time of calculation. Individual fuel costs will vary depending on driving habits, local fuel prices, and the type of fuel used. However, $2,250 provides a useful benchmark for understanding the potential fuel expenses associated with owning and operating this particular model.

Real-world expectations

While EPA estimates provide a standardized benchmark, real-world fuel economy can differ. Aggressive driving, frequent stop-and-go traffic, and carrying heavy loads can all reduce fuel efficiency. On the other hand, smooth acceleration, consistent speeds, and proper tire inflation can improve MPG. CLS450 drivers who prioritize fuel conservation can expect to see figures close to the EPA estimates. Those who regularly drive it hard may experience lower MPG. Understanding the factors that influence fuel economy helps drivers to optimize their driving habits and minimize fuel consumption.

How it compares

The 2020 CLS450’s fuel economy positions it competitively within its class. The Audi A7, another stylish four-door coupe, achieves a similar 25 MPG combined with its 3.0-liter V6. The BMW 840i Gran Coupe, while offering more horsepower, returns around 25 MPG combined. The Porsche Panamera, known for its performance, offers a wide range of MPG figures depending on trim, with some models falling slightly below the CLS450’s efficiency. For buyers considering vehicles in this segment, the CLS450 strikes a solid balance between fuel economy and performance. Data on all Mercedes Benz fuel economy data, including the CLS450 MPG across all years, reveals the consistent approach to efficiency within the lineup.

Tips to maximize efficiency

Use the CLS450’s drive modes. Selecting “Comfort” or “Eco” mode will prioritize fuel efficiency by adjusting the throttle response, transmission shift points, and other vehicle parameters. These modes encourage smoother and more relaxed driving, which ultimately reduces fuel consumption.

Maintain proper tire inflation. Underinflated tires increase rolling resistance, and this lowers fuel economy. Check your tire pressure regularly and inflate them to the recommended pressure specified on the doorjamb sticker. This simple step can noticeably improve MPG.

Minimize idling. Excessive idling wastes fuel, particularly in modern engines. If you anticipate waiting for more than a minute, turn off the engine. The CLS450’s mild-hybrid system offers a smooth restart, and you’ll save fuel in the process.

Anticipate traffic flow. By anticipating traffic conditions, you can avoid sudden braking and acceleration, which negatively impacts fuel economy. Maintain a safe following distance and try to maintain a consistent speed whenever possible. Planning your route to avoid congested areas can also save fuel.